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Sepsis is an illness that affects nearly 50 million people worldwide each year, with around 11 million deaths attributed to the condition. In the United States, at least 1.7 million adults in the US develop sepsis annually, and nearly 270,000 die as a result, the Centres for Disease Control and Prevention (CDC) says. It affects 245,000 people in the UK each year, with around 48,000 deaths, according to the UK Sepsis Trust. World Sepsis Day commemorated on 13th September every year, strives to raise global awareness of the life-threatening condition. The day is seen as “an opportunity for people worldwide to unite in the fight against sepsis,” the Global Sepsis Alliance says. Here is everything you need to know about sepsis: What is sepsis? Sepsis Research says when the condition strikes, the immune system “overreacts” and begins to attack the infection and everything else around it “including the body’s own tissues and organs.” “Any type of infection — bacterial, viral or fungal — can lead to sepsis,” it adds. When sepsis occurs, it can cause inflammation and cause blood clotting around the body, if it does not get treated, it can result in death, organ failure and tissue damage, CDC says. Sepsis cannot be caught from another person, the NHS explains. What are the symptoms? The World Health Organisation (WHO) explains that the condition is a “medical emergency,” so if you think a person is exhibiting signs of sepsis or if you are showing signs – make sure you call 999 or go to the emergency room immediately. According to WHO, common signs and symptoms include: • Fever or low temperature and shivering • Confusion • Difficulty breathing • Clammy or sweaty skin • Extreme body pain or discomfort • High heart rate, weak pulse or low blood pressure • Low urine output Symptoms in children include: • Fast breathing • Convulsions • Pale skin • Lethargy • Difficulty waking up • Feeling cold to touch What are the causes? The Mayo Clinic says any type of infection can lead to sepsis and those that more commonly cause the condition include infections of: • Lungs, such as pneumonia • Kidney, bladder and other parts of the urinary system • Digestive system • Bloodstream • Catheter sites • Wounds or burns “Sepsis often presents as the clinical deterioration of common and preventable infections such as those of the respiratory, gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently under-diagnosed at an early stage - when it still is potentially reversible,” the Global Sepsis Alliance says. Who is most at risk? The people most at risk of the condition, according to Mayo Clinic, are: • People with lower immune response, such as those being treated for cancer • People with human immunodeficiency virus (HIV). • People with chronic diseases such as diabetes kidney disease or chronic obstructive pulmonary disease (COPD). • people who are in intensive care or longer hospital stays. • People over the age of 65 • Infants How many cases are there globally? The WHO says a scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20 per cent of all global deaths. That same year, almost half of all global sepsis cases occurred among children with an estimated 20 million cases and 2.9 million global deaths in children under 5 years of age. How can it be prevented? The Global Sepsis Alliance says the best to to avoid sepsis is by preventing infection. This can be done by undergoing vaccinations, ensuring that you only come into contact with clean water, washing your hands properly and if you are giving birth - making sure it is in a clean and sterilised environment. Can sepsis be treated? Sepsis can be treated with appropriate treatment such as antibiotics – this should be given as soon as possible. The CDC says sometimes “surgery is required to remove tissue damaged by the infection”. “Antibiotics are critical tools for treating life-threatening infections, like those that can lead to sepsis,” the CDC adds. Read More 5 things everyone needs to know about eczema 13 potential cancer symptoms you should get checked out How can I improve my teenager’s low mood? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis Nine hours of parallel surgery: how Britain’s first womb transplant was carried out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’

A new leak claims Call of Duty 2025 will be a continuation of Treyarch's Call of Duty 2024 and feature remastered Black Ops 2 maps like Raid, Standoff, and Slums.

Credits are an essential part of Starfield. Here's a glitch that will get you infinite money in the game.

Joe Biden had to spend a couple of hours in Alaska as he stopped for refueling on his way back from Vietnam and India

The Moroccan community appeals for aid to send to families impacted by the disaster.

An Indiana man was jailed for 110 years for gunning down his ex-girlfriend and her grandmother in front of each other in a parking lot. Gary Cecil Ferrell II, 28, will spend the rest of his life in a state correctional facility for the murders of 21-year-old Promise Mays and 62-year-old Pamela Sledd. Prosecutors say that the August 2021 killings were captured by security cameras at an automotive seating factory in Frankfort. Clinton Superior Court Judge Justin Hunter wrote in his sentencing order that the crime had been “brutal and heinous” and it was appalling that the victims had “watched the other being shot.” “With respect to the murder he inflicted upon Pamela Sledd, defendant shot Ms Sledd after she had turned her back and was retreating from the scene of the offense she had witnessed against her granddaughter,” he wrote in the document, reported WISH-TV. “[Ferrell] acted out an entitlement to control and possess Promise Mays, whether in life or in death, even though she had demonstrated only kindness for the many people whom she encountered in her short and precious life.” Both women were killed with a semiautomatic handgun as they had arrived for their work shift at the NHK factory. Police quickly identified Ferrell as the suspect and eventually caught him after he crashed his vehicle in a construction zone. Ferrell was sentenced to serve 45 to 65 years for each count of murder, running consecutively. He must serve at least 80 years before he is eligible for release. Read More Police officer jailed for one year for stomping on handcuffed man’s face during arrest Boy, 5, accidentally kills himself after caretaker with gun falls asleep Prosecutor asks Indiana State Police to investigate dog deaths in uncooled rear of truck

Officials from the City of Atlanta have refused to verify tens of thousands of signatures submitted by activists who have been trying for two years to stop the construction of a police and firefighter training center

U.S. regulators have approved updated COVID-19 vaccines from Pfizer and Moderna, shots aimed at revving up protection this fall and winter

Dolly the sheep was the first animal cloned from a single adult cell—and raised a lot of questions about the future of human cloning.

The British foreign secretary has arrived in Israel on a three-day visit to a country in turmoil, facing its biggest protest movement in history and heightened violence in the occupied West Bank

WASHINGTON Washington expects U.S. Secretary of State Antony Blinken will host China's Foreign Minister Wang Yi in the

The Londonderry School Board unanimously voted to suspend the high school's cheerleading program without any further delay