
Google AI breakthrough represents huge step in finding genes that cause diseases, scientists say
Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss
2023-09-20 00:25
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US lawmaker to urge chip industry group to reduce China investments -source
By Stephen Nellis The chair of the U.S. House of Representatives' committee on China on Tuesday planned to
2023-09-19 21:50
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The iPhone's new Action Button is more than a one-trick pony
The new iPhone 15 Pro lineup offers a lot to get excited about: They're slimmer and thinner, the new cameras are professional-grade and the switch to USB-C charging will make your life easier. But one new feature easily stands out as the most fun: The Action Button.
2023-09-19 21:28
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BBC removes some Russell Brand content as monetisation suspended on YouTube
YouTube has stopped Russell Brand making money on its platform because of the rape and sexual assault allegations made against him. The Google-owned company said it has suspended the monetisation of the 48-year-old’s channel because he was “violating” its “creator responsibility policy”. The BBC has also announced it was removing some content from its iPlayer and Sounds apps which “now falls below public expectations”. An episode of QI and a Joe Wicks podcast, both featuring Brand as a guest, have been removed, the PA news agency understands. It comes as the Commons Culture, Media and Sport Committee chairwoman Dame Caroline Dinenage has written to the BBC, Channel 4 and TikTok to request for further details on what actions they are taking in response to the allegations and to GB News in relation to their coverage of the claims. Brand’s YouTube account, which has 6.6 million subscribers, has been suspended from YouTube’s Partner account “following serious allegations against the creator”, meaning the channel is no longer able to make money from advertising on the platform. In a statement, YouTube said the decision applied to all channels that may be “owned or operated” by Brand, adding: “If a creator’s off-platform behaviour harms our users, employees or ecosystem, we take action to protect the community.” The news comes after the remaining shows of Brand’s Bipolarisation tour were postponed and the Metropolitan Police said they had received a report of an alleged sexual assault in the wake of media allegations about the comedian and actor. A BBC spokesperson said: “The BBC does not ban or remove content when it is a matter of public record, unless we have justification for doing so. “There is limited content featuring Russell Brand on iPlayer and Sounds. We’ve reviewed that content and made a considered decision to remove some of it, having assessed that it now falls below public expectations.” Dame Caroline has said: “This weekend we have seen some very serious and disturbing accusations about Russell Brand’s behaviour and we understand that the police are now looking into some of these allegations. “As a first step, our committee has decided that we will today write to media outlets, including the BBC and Channel 4, to understand the actions they are taking as we consider some of the issues around these allegations.” In separate letters to Channel 4 chief executive Alex Mahon and BBC director-general Tim Davie, the committee chairwoman asked for a timescale and regular updates on their internal investigation. The letters also requested updates on the investigation being conducted by Banijay UK, which bought Endemol, the company commissioned by Channel 4 to produce the Big Brother spin-off shows Brand hosted, into his behaviour while he was working on their programmes. She added: “We urge both the BBC and Channel 4 to do everything possible not only to ensure that employees, contributors and suppliers feel safe at work, but also create an environment whereby people can speak out when procedures are breached.” Meanwhile, TikTok’s director of Government relations, Theo Bertram, was asked whether Brand could monetise his posts on the video sharing platform, where he has 2.3 million followers. Dame Caroline also asked “what the platform is doing to ensure that creators are not able to use the platform to undermine the welfare of victims of inappropriate and potentially illegal behaviour”. Brand still has a presence on video platform Rumble, where his channel has 1.4 million followers and he hosts a weekly live show at 5pm BST, but there was no new episode on Monday. His most recent video on Rumble is the short clip from Friday when he denied the allegations against him, which were published the following day. His Rumble channel description reads: “Everybody knows that the old ideas won’t help us. Religion is dead. Capitalism is dead. Communism is dead. Where will the answers of the next century lie? Particularly, when we’re facing a mental health epidemic and ecological meltdown.” He also has a dedicated subscribers’ area on the online community platform Locals, where members can sign up for a minimum 60 US dollars (£48) a year – or enter a higher amount if they wish to donate more – in order to access special bonus content from Brand, as well as the opportunity to interact with him directly. Brand has been accused of rape, assault and emotional abuse between 2006 and 2013, when he was at the height of his fame and working for the BBC, Channel 4 and starring in Hollywood films, following a joint investigation by The Times, Sunday Times and Channel 4’s Dispatches. He has strongly denied the allegations, which also include claims of controlling, abusive and predatory behaviour. His YouTube channel includes coverage of news stories, including alleged misinformation surrounding the Covid-19 pandemic and being an outspoken sceptic of the vaccine. Last year, one of his videos was taken down on YouTube over the site’s policy on Covid-19 disinformation, which prompted Brand to move his channel to Rumble. On Tuesday, The Times reported that several other women have since come forward with fresh claims about Brand. One woman, using the fake name Lisa, told the paper the comedian had sung about Soham killer Ian Huntley during a consensual sexual encounter in 2008. Another woman, known as Esme, told The Times that Brand had been threatening and verbally abusive towards her when she refused to have sex with him. In a now deleted YouTube video, Brand can be heard joking about raping a woman during a recording of Richard Herring’s Leicester Square Theatre Podcast in 2013. Before the first allegations were published, Brand posted a video on Friday saying he has been “promiscuous” but that all of his relationships have been “consensual”.
2023-09-19 21:20
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Britain invites China to AI summit
LONDON Britain has invited China to its Artificial Intelligence Safety Summit in November, foreign minister James Cleverly said
2023-09-19 21:16
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YouTube cuts off Russell Brand's ad revenues after sexual assault allegations
LONDON (Reuters) -YouTube said on Tuesday it had blocked Russell Brand from making money from his online channel after the
2023-09-19 20:50
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Coinbase kicks off grassroots campaign to advance US legislation
By Hannah Lang Coinbase, the largest U.S. cryptocurrency exchange, is stepping up its grassroots advocacy campaign in a
2023-09-19 19:19
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Google rolls out a major expansion of its Bard AI chatbot
Google's Bard artificial intelligence chatbot is evolving.
2023-09-19 18:51
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Google announces new Bard features as traffic continues to lag ChatGPT
By Anna Tong Alphabet Inc's Google said on Tuesday that Bard, its generative artificial intelligence, will have the
2023-09-19 18:29
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Monetisation of Russell Brand’s YouTube channel suspended
YouTube has suspended the monetisation of Russell Brand’s channel for “violating” its “creator responsibility policy”. In a statement to the PA news agency, a spokesperson for the Google-owned company said: “If a creator’s off-platform behaviour harms our users, employees or ecosystem, we take action to protect the community.” The news comes after the remaining shows of Brand’s Bipolarisation tour were postponed and the Metropolitan Police said it had received a report of an alleged sexual assault in the wake of media allegations about the comedian and actor. Brand’s YouTube account, which has 6.6 million subscribers, has been suspended from YouTube’s partner account “following serious allegations against the creator”, meaning the channel is no longer able to make money from advertising on the platform. The statement added: “This decision applies to all channels that may be owned or operated by Russell Brand.” The 48-year-old actor has been accused of rape, assault and emotional abuse between 2006 and 2013, when he was at the height of his fame and working for the BBC, Channel 4 and starring in Hollywood films, following a joint investigation by The Times, Sunday Times and Channel 4’s Dispatches. He has strongly denied the allegations, which also include claims of controlling, abusive and predatory behaviour. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live
2023-09-19 15:25
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Arizona governor says state in talks with TSMC on advanced packaging
By Sarah Wu TAIPEI (Reuters) -The U.S. state of Arizona is in talks with Taiwanese chipmaker TSMC on advanced packaging,
2023-09-19 13:59
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Elon Musk says Twitter to move behind paywall as all users forced to pay ‘small’ monthly fee
Elon Musk said X is looking to charge users a “small monthly payment” to tackle bots on the social network. X, previously known as Twitter, underwent a number of changes soon after Mr Musk, the multibillionaire owner of X Corp, bought it. The platform is now “moving to having a small, monthly payment for use of the X system” to combat “vast armies of bots”, Mr Musk said during a livestreamed conversation with Israeli prime minister Benjamin Netanyahu on Monday. However, the Tesla and SpaceX boss did not reveal how much the new plan would cost X users or what additional features subscribers would get. During the interaction with Mr Netanyahu, the Tesla titan said X currently has 550 million “monthly users” who generate 100-200 million posts per day, adding that the new change to include a “small amount of money” would be necessary to deal with the problem posed by bots. It is unclear whether the multibillionaire’s figure of 550 million monthly users includes bots and also doesn’t allow comparison with the metric the company has used to estimate its user base, called the “average monetizable daily active users” or mDAUs. But the Tesla chief said a subscription fee would make it more difficult for bots to create accounts as each bot would need a new credit card to register on the platform. “It’s the only way I can think of to combat vast armies of bots,” Mr Musk said. “Because a bot costs a fraction of a penny – call it a tenth of a penny – but even if it has to pay a few dollars or something, the effective cost of bots is very high,” he explained. The platform has historically struggled to curb the activity of bots, with the company’s former security chief Peiter Zatko telling the US Congress last year that Twitter does not even know how many automated accounts are on the site. Mr Musk even cited bots as a reason to back out of buying the social platform before he went on to complete the deal. He has also previously discussed putting all of Twitter behind a paywall. Now the Tesla boss says the rebranded X plans to introduce a new “lower tier pricing” than the $8 monthly fee it currently charges subscribers of its premium Blue service. The conversation between Mr Musk and the Israeli prime minister also touched on topics like AI regulation as well as hate speech and antisemitism on X. Mr Musk claimed during the discussion that he’s “against antisemitism” and “anything that promotes hate and conflict”. “I’m sort of against attacking any group, you know. Doesn’t matter who it is,” the Tesla chief said. Online safety experts have warned about the social media platform under “free speech absolutist” Mr Musk offering “amnesty” to accounts previously suspended for hate speech and instigating violence. Under the Tesla titan, the platform restored the account of former US president Donald Trump who was banned following the 2021 Capitol riots, as well as the profiles of Republican Marjorie Taylor Greene and neo-Nazi website founder Andrew Anglin. Read More The ex factor: the very complex love life of Elon Musk Netanyahu visits Elon Musk in California with plans to talk about artificial intelligence Turkey's President Erdogan and Elon Musk discuss establishing a Tesla car factory in Turkey Elon Musk’s X finally agrees to try and settle Twitter’s mass layoffs lawsuit Musk the messiah (or a very naughty boy?) Elon Musk warns of ‘civilisational risk’ posed by AI at historic gathering
2023-09-19 13:26