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Andre Onana failed to deal with two Hakim Ziyech free-kicks as Manchester United threw away a two-goal lead against Galatasaray on Wednesday night. It was the latest Champions League drama for the much-scrutinised goalkeeper and here, the PA news agency looks at his United record. Champions League roller coaster The 3-3 draw in Istanbul followed a 3-2 defeat in the first meeting with Gala and 4-3 losses to Bayern Munich and FC Copenhagen as United, top scorers in Champions League Group A, prop up the standings. That contributes to Onana’s record of 33 goals conceded in 20 games since Erik ten Hag signed him from Inter Milan this summer to replace long-serving keeper David De Gea. He has conceded only 16 in 13 Premier League appearances – a slight improvement on De Gea’s record under Ten Hag at the same stage of last season, when he had conceded 18 – but remarkably has topped that in only seven appearances in other competitions, which also include a 3-0 Carabao Cup loss to Newcastle. By this date last season, United had conceded 25 goals in 21 games in all competitions – De Gea accounting for 23 in 20, albeit with his European appearances coming in the Europa League. Martin Dubravka was in goal for the 4-2 League Cup win over Aston Villa. One extreme or the other Onana has seven clean sheets with United, including a stoppage-time penalty save in the 1-0 home win over Copenhagen, but has conceded three or more on eight occasions – De Gea did so only six times the whole of last season, though they included losing 6-3 to Manchester City and 7-0 to Liverpool. United have this season lost league games 3-1 to Arsenal and Brighton and 3-0 to City, in addition to the Newcastle tie and the four Champions League games. Eight games represent 40 per cent of Onana’s United appearances to date, while De Gea conceded three or more in less than 10 per cent of games over his 12 years at Old Trafford. That ‘one extreme or the other’ approach this season leaves only five exceptions in which United have conceded either once or twice. They have four clean sheets and have conceded three or four in their other four games since beating Sheffield United 2-1 on October 21. How Onana compares De Gea won last season’s Premier League Golden Glove with 17 clean sheets and conceded 43 goals in 38 games, an average of 1.13 per game. Onana’s current rate of 1.23 would equate to 46.77 goals over the full league season – only twice have United conceded 47 or more, 54 in 2018-19 and 57 in 2021-22. De Gea was ever-present in the league for both of those seasons, comfortably United’s worst in the Premier League era. In 2018-19 they conceded 72 in 51 games in all competitions, an average of 1.41 per game. Last season, Ten Hag’s first in charge, United conceded 63 goals in 62 games overall – 1.02 per game. De Gea was ever-present apart from four Carabao Cup games shared between Dubravka and Tom Heaton. In mitigation for Onana, United have allowed more shots on target this season while dealing with injuries in defence. The Cameroon international has made 51 saves in 13 league games, already halfway to De Gea’s tally of 101 in 38 last term and averaging 3.9 per game, up from 2.7. Read More Lancashire sign Australia off-spinner Nathan Lyon for 2024 season We have to own it – Scott McTominay urges Man Utd to atone for Galatasaray draw Keira Walsh ‘feeling fresh’ before latest round of Women’s Nations League games He’s amazing – Martin Odegaard hails ‘brilliant’ Declan Rice impact at Arsenal On This Day in 2004 – Sir Matthew Pinsent announces retirement from rowing Arsenal through to last 16 as Manchester United squander lead again

Our canine companions could soon be enjoying much longer lifespans, if a drug which claims it can extend dogs’ lives eventually gets approved. The drug, made by a tech firm in California, just cleared a vital hurdle to doing just that, after it got partial approval by regulators in the US. Loyal, a San Francisco-based company founded in 2020, has been researching how it can increase dogs’ lifespans – in particular larger breeds, which tend to die younger. Large and “giant” breeds tend to live to between eight and 12 years. Smaller dogs, such as Chihuahuas, can keep going to the ripe old age of 20. Loyal’s main product, the catchily-titled LOY-001, is designed not only to extend dogs’ lives but also maintain their quality of life. Now, it has passed the “reasonable expectation of effectiveness” test, set by regulators at the US’ Food and Drug Administration. Loyal’s chief executive, Celine Halioua, said: "Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs. "This milestone is the result of years of careful work by the team. We'll continue to work just as diligently to bring this and our other longevity programs through to FDA approval." Selective breeding of dogs has caused higher levels of hormones which help the animals grow faster. That is also believed to reduce their lifespan, the company said. Big dogs tend to have more of this hormone than their smaller counterparts. Animal rights activists are not yet convinced. Some experts fear it will only serve to extend animals’ suffering. Loyal, on the other hand, says the drug aims to treat doggy diseases which are associated with ageing through preventing them, rather than waiting for the animals to get sick before treating them. The company said that the drug could be available to US customers as early as 2026. So that’s plenty of time for walkies between now and then. How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

A look at the day ahead in U.S. and global markets from Mike Dolan The best month of the year

By Tim Reid and Alexandra Ulmer U.S. presidential candidate Ron DeSantis will use a televised debate against California's

Rodrygo admits he is unsure what the future holds for Carlo Ancelotti at Real Madrid amid interest from Brazil.

By Lisa Baertlein and Arriana McLymore LOS ANGELES/NEW YORK As holiday shoppers return items purchased during Black Friday

By John Kruzel and Andrew Chung WASHINGTON Senate Democrats are expected on Thursday to vote on authorizing subpoenas

By Akash Sriram and Hyunjoo Jin Tesla is set to start deliveries of its long-delayed Cybertruck electric pickup

As Palestinians celebrated Israel’s release of prisoners outside Ramallah’s sand-colored municipality last Friday, green Hamas flags dotted the

Chess.com has given an official verdict on the cheating allegations made against Hikaru Nakamura, after the grandmaster and streamer found himself at the centre of the biggest drama in the sport. In case you’ve not been following the story over the last week or two, Nakamura dismissed “garbage” claims that he had cheated recently after going on a 15-game winning streak. Grandmaster Vladimir Kramnik added fuel to the fire after the claims came to light on social media – and even though Kramnik later deleted the posts about Nakamura, he didn’t take it lightly at all. Now, Chess.com has waded in on the news story and completely absolved Nakamura. Addressing the claims, the site said in a statement: “In the case of the recent accusations against Hikaru Nakamura by Vladimir Kramnik, we can say that we have generated nearly 2,000 individual reports on Hikaru’s games in our Fair Play system and have found no incidents of cheating.” “Our team has done the math and various simulations of streaks for a player like Hikaru who has played more than 50,000 games. We have found that not only is a 45 game winning streak possible, it is in fact likely given the number of games played,” the site added. Not finished there, Chess.com went on to say that the claims “lack statistical merit” having consulted statisticians. However, cheating is far more prevalent on the platform than people might think. According to Chess.com, 50,000 accounts were banned for cheating on the platform in October alone. Sign up for our free Indy100 weekly newsletter How to join the indy100's free WhatsApp channel Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings

Mikel Arteta admits Arsenal's 6-0 win over Lens in the Champions League felt like a dream.

By Foo Yun Chee BRUSSELS (Reuters) -Meta Platforms' advertising-free subscription service, a fee-based offering rolled out in Europe this month,