List of All Articles with Tag 'p'

The Justice Department says a witness in the federal prosecution of Donald Trump over the hoarding of classified documents retracted “prior false testimony” after switching lawyers last month and provided new information that implicated the former president

Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. Read More Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out

Michael Beale insists Rangers’ Champions League hopes should not be written off following the 2-2 play-off draw with PSV Eindhoven at Ibrox. Gers attacker Abdallah Sima curled in a terrific first-leg opener just before the interval but the Dutch side levelled through midfielder Ibrahim Sangare just after the hour mark. As play raced from end to end, substitute Rabbi Matondo scored his first Light Blues goal in the 76th minute before PSV captain Luuk de Jong levelled with a header four minutes later, and the match ended in a repeat of last year’s score at the same stage of the competition. The two sides drew 2-2 at Ibrox before Rangers scrambled a 1-0 win in Eindhoven and Beale remains confident of progress in the Netherlands next Wednesday night. Asked if lightning can strike twice against the Dutch side, Beale said: “I think so, yes, of course. Naturally we will go across and be extremely positive. “There were moments of tonight’s game when I thought we were very good. “I thought we scored two good goals and all night we caused them problems defensively. There were areas of the game we’d want to improve on, for sure. But everything is to play for. “We wanted to set up next week and we’ve done that. “Tonight when we were struggling, we fought for each other. We ran for each other, we problem-solved on the pitch. “This new group are learning very quickly that big nights like tonight bring us together. “I don’t want anybody to underestimate us next week because it’s in this club to go put this performance on. “We’ll have our thousands of fans travelling over there and as a team we’re going there to get this job done and we will give it everything we can. “I think the tie is evenly set. I don’t think them and their coach are travelling home thinking ‘this is a job done’. “They will know how hard physically that game was, at the end it looked like they had one or two bumps and bruises as well. It is finely poised. “I think the two penalty boxes are going to be decisive. It’s important you play well between them but the most important thing is you take your chances when they come.” PSV boss Peter Bosz was left with “mixed feelings” but is confident of finishing the tie next week. He said: “I am never afraid of anything. I always think ‘go for it’. “Even if I was there last season (when Rangers won), my mentality would be that this season we are going to make it. “I felt we would be dominating here and they would play the counter-attack real well and really fast. “That is how they scored their second goal. They had the energy of the crowd. “We have to play a lot better in the return or we will not make it through. What do we need to do? Score more goals and don’t let stupid goals go in against us.”

A federal judge has ordered Mississippi’s largest electric utility to turn over information on customers in and around the capital city who might be using water without paying for it

Travelers taking off and landing at Dulles International Airport outside the nation’s capital will soon see an array of 200,000 solar panels that comprise the largest renewable energy project ever built at a U.S. airport

The Los Angeles Dodgers have placed designated hitter J

Race car driver Ashlea Albertson was on track to compete at a championship event in Indiana on Saturday. A few months later, she would make her way down the aisle at her wedding. But instead, the 24-year-old’s life was cut short on Friday morning in an apparent road rage crash away from the track. Albertson, who drove for the Tony Stewart Racing team, was a passenger in a 2018 GMC Terrain that crashed at around 11.30am on I-65 in Jackson County just south of Seymour, Indiana. The SUV, which was being driven by her fiancé Jake Kelly, 31, crashed after a 2016 Chevrolet Malibu pulled up in the right lane and both vehicles began accelerating, each refusing to let the other pass, according to the Indiana State Police. The two vehicles collided, causing the SUV to flip over, ejecting Albertson. She was flown to the University of Louisville Hospital where she died from her injuries. The next day, the rising star’s No 4 race car sat empty at the All Star Circuit of Champions TQ Midgets event in Shelbyville, Indiana, but was surrounded by flowers and messages left by her loved ones and fans. It was her family’s wish for the race to go on as planned at the Shelby County Fairgrounds, with her father Todd Albertson telling the local Indianapolis station WTHR, “We have to do better.” “She lost her life not on a race track, where we thought she might, but in the middle of a highway because we can’t control our anger,” Mr Albertson said. Famed race car driver Tony Stewart, who is now semi-retired, described Albertson as having an “infectious personality” and the ability to “light up a room.” “She was a great race car driver that was involved in a road rage accident and lost her life,” Stewart wrote in a social media post. “In the past, I’ve also gotten caught up in road rage. I hope that we can honor Ashlea by controlling what we can control on the highway. Losing her is a sobering reminder of how precious life is.” Loved ones said Albertson was “fearless on and off the race track” and that she was “exceptional in a male-dominated sport.” Albertson, who was fourth in the All Star Circuit of Champions standings out of 39 listed drivers going into last weekend’s race, would have been the only female driver on the track that night, her coach Ron Combs said. Mr Combs, who is also an All Star Circuit of Champions official, told local news that her car won’t be raced any more this year, but added that he hopes to see another woman with her dream get behind the wheel someday. “I’m going to think about Ashlea every time I think I’m going to have road rage,” Mr Combs added. “Ashlea will be in the back of my head. Stop, slow down, and do what’s right.” A spokesman for the Indiana State Police told The Washington Post he would “hesitate” to use the phrase “road rage,” then added that “the evidence indicates that both drivers involved in the incident displayed some aggressive driving that appeared to contribute to the crash.” Video recorded by an occupant in another vehicle showed that Mr Kelly, the driver of the SUV, and the driver of the Malibu, 22-year-old Austin Cooper, began accelerating rapidly and refused to allow the other pass on the two-lane road, state police said. The Malibu suddenly changed lanes right into the SUV’s path and the two vehicles collided, causing it to crash. Both drivers submitted to blood tests and toxicology results are pending, state police said. Albertson was to be married to Jake Kelly in March, according to her obituary. “The wedding dress was purchased and their children’s names had been chosen,” it stated. “The impact Ashlea made on those she came in contact with was strong and deep.” Albertson had been a competitive race car driver since 2011 and landed the All-Star Circuit of Champions TQ Midget series in 2017. She had several feature wins and many podium finishes, while driving for Tony Stewart Racing. “The race track was clearly her favorite place to be,” the obit stated. Following her passing, Albertson’s father posted an emotional video on Facebook. “This is one of the hardest posts that I could possibly make, but I have no words to put it out other than making a video to share with everybody who loved her and that she loved in return,” he said tearfully. “I want to thank you from my family, from myself, for making her feel like she was the best racer out there each and every time that she took the track. “We appreciate you. We love you. I’m sorry to inform you this way, but it’s only fair that everybody knows and there be no speculation moving forward. “She was a good kid, a better person. She just loved racing, she loved the community and you all have done so much for her. Thank you, from the bottom of my heart. Please keep my family, her fiancé, and everybody that is going through this time in your thoughts and prayers. “Those of you who go to the track this weekend and enjoy racing, please know that’s all she ever wanted to do was put on a show … and be loved and respected by each and everyone of you that followed her. … Enjoy life and every moment that it is. It’s precious. We never know when our time is.” A Celebration of Life Service will be held on Sunday at New Palestine United Methodist Church, in New Palestine, Indiana. Attendees are encouraged to wear racing shirts and cheery clothing, as Alberston would prefer, according to her obit. Read More Tony Stewart Racing driver, 24, killed in ‘road rage’ incident on Indiana highway An Ohio school bus overturns after crash with minivan, leaving 1 child dead and 23 injured A teenager killed her boyfriend and his friend in a ‘hell on wheels’ crash. She will serve 15 years to life

The former head of Brazilian retailer Americanas quit two weeks into the job because he had not expected

The New York Yankees have added some youth by recalling outfielder Everson Pereira and infielder Oswald Peraza from Triple-A Scranton/Wilkes Barre

Court hearings are underway to determine whether a new Missouri law banning minors from receiving gender-affirming health care will take effect as scheduled Monday

By Yelin Mo, Max A. Cherney and Stephen Nellis The upcoming listing of semiconductor technology firm Arm Holdings

The parks offer thrill seekers, ghost hunters, and the brave alike another reason to visit.