List of All Articles with Tag 'ie'

AbbVie said on Thursday it will buy drugmaker ImmunoGen for $10.1 billion, boosting its presence in the market

Radiohead drummer Philip Selway has hinted that the band are ready to reunite after being on hiatus since 2018.

Our canine companions could soon be enjoying much longer lifespans, if a drug which claims it can extend dogs’ lives eventually gets approved. The drug, made by a tech firm in California, just cleared a vital hurdle to doing just that, after it got partial approval by regulators in the US. Loyal, a San Francisco-based company founded in 2020, has been researching how it can increase dogs’ lifespans – in particular larger breeds, which tend to die younger. Large and “giant” breeds tend to live to between eight and 12 years. Smaller dogs, such as Chihuahuas, can keep going to the ripe old age of 20. Loyal’s main product, the catchily-titled LOY-001, is designed not only to extend dogs’ lives but also maintain their quality of life. Now, it has passed the “reasonable expectation of effectiveness” test, set by regulators at the US’ Food and Drug Administration. Loyal’s chief executive, Celine Halioua, said: "Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs. "This milestone is the result of years of careful work by the team. We'll continue to work just as diligently to bring this and our other longevity programs through to FDA approval." Selective breeding of dogs has caused higher levels of hormones which help the animals grow faster. That is also believed to reduce their lifespan, the company said. Big dogs tend to have more of this hormone than their smaller counterparts. Animal rights activists are not yet convinced. Some experts fear it will only serve to extend animals’ suffering. Loyal, on the other hand, says the drug aims to treat doggy diseases which are associated with ageing through preventing them, rather than waiting for the animals to get sick before treating them. The company said that the drug could be available to US customers as early as 2026. So that’s plenty of time for walkies between now and then. How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

A look at the day ahead in U.S. and global markets from Mike Dolan The best month of the year

COP28 Daily Reports: Sign up for the Green Daily newsletter for comprehensive coverage of the climate summit right

Radio presenter Jeremy Vine has given listeners perhaps the most quintessentially “Alan Partridge” moment when reading out a surprisingly morbid story on his BBC Radio 2 show. Vine, 58, was telling a tale about an eight-year-old who was boating with their family on the River Hull live on his show. While reading up to the point when the writer’s 12-year-old brother took control of the boat and drove it into a bridge, he started laughing. “I don’t know why I’m laughing,” he said. The contents of the letter, however, were about to get extremely dark. Vine, reading out the story, said: "When I was eight, my parents had a boat on the River Hull, one day it rained and the river rose, my parents let my 12-year-old brother drive the boat. “We were sunbathing on deck, I went to get a drink just as the galley caved in, because what he'd done is accelerated..." Chuckling, Vine continued: "...into Tickton Bridge... I don't know why I'm laughing....okay, this is not good. "The collision took my mum's arm off...blimey O'Riley... I didn't see that coming.” The listener wrote that they would have been "decapitated" if they had still been on the boat's deck. Jeremy ended with: "Okay...well that's slightly lowered the mood." Sharing the post on social media, one listener said: “Purest Alan Partridge moment from Vine, here. Gold.” Vine responded: "I can only apologise." Oops. How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Remy Cointreau SA’s first-half profit missed analyst expectations amid a sharp decline in US demand for its pricey

Sebastian Stan has been cast as a young Donald Trump in Ali Abbasi's biopic 'The Apprentice'.

MBC Group, the Middle East’s biggest broadcaster, received more orders than shares available for its initial public offering

Nigeria will spend at least six times more on servicing its debt next year than on building new

The Dutch government plans to sell shares worth about €1 billion ($1.1 billion) in ABN Amro Bank NV

Germany’s unemployment rate unexpectedly rose to the highest level in 2 1/2 years, a sign that the weakness