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Adults who spend a large part of their day engaging in sedentary behaviors are more prone to dementia, a new study finds. The research, published on Monday in the journal JAMA, found that people aged 60 and older who spend over 10 hours a day engaging in behaviors like sitting while watching TV or driving could be at increased risk of developing dementia. Scientists, including those from the University of Southern California say, the findings are concerning since Americans on average are sedentary for about 9.5 hours each day. In the study, researchers assessed the data from about 50,000 adults over the age of 60 who had wrist-worn accelerometers to measure their movement for 24 hours per day for a week. The individuals did not have a diagnosis of dementia at the start of the study, scientists noted. They then used a machine-learning algorithm to analyse the dataset of accelerometer readings and classify behaviors based on different intensities of physical activity. Using the AI system, scientists could differentiate between different types of activity and sleeping – providing an objective measure of the time each person spent engaging in different types of sedentary behaviors. After an average of six years of follow-up, researchers used hospital records and death registry data to determine dementia diagnosis, and found 414 participants had the neurological condition. Scientists then adjusted for factors such as age, sex, education level, race/ethnicity, chronic conditions, genetics as well as lifestyle characteristics like physical activity, diet, smoking and alcohol use, self-reported mental health. They found that sedentary behavior was linked with increased risk of dementia among the participants. However, they found that certain amounts of sedentary behavior was not associated with dementia. “We were surprised to find that the risk of dementia begins to rapidly increase after 10 hours spent sedentary each day, regardless of how the sedentary time was accumulated,” study author Gene Alexander from the University of Arizona said. “This suggests that it is the total time spent sedentary that drove the relationship between sedentary behavior and dementia risk, but importantly lower levels of sedentary behavior, up to around 10 hours, were not associated with increased risk,” Dr Alexander added. Researchers call for more studies to establish causality and whether physical activity can mitigate the risk of developing dementia. The findings, according to scientists, “should provide some reassurance to those of us with office jobs that involve prolonged periods of sitting, as long as we limit our total daily time spent sedentary”. Read More What it’s like having Menopause Brain in a millennial office Josh Duhamel and wife Audra Mari announce they’re expecting first baby together Woman warns not to ignore symptoms after hot flushes lead to leukaemia diagnosis Poor metabolic health ‘linked with 12% higher risk of dementia later in life’ Sleeping pill could reduce levels of Alzheimer’s proteins Daily aspirin dose can help prevent diabetes in older people, scientists say

Ange Postecoglou is excited to welcome Yves Bissouma back into the fold for Sunday’s trip to Manchester City, but admits Tottenham must improve their discipline. Bissouma is available again after serving a one-match ban against Aston Villa for receiving five yellow cards before the halfway point of the Premier League season. The former Brighton midfielder enjoyed a superb start to the new campaign but has only played three times since being sent off for two bookings at Luton in early October. Bissouma is not alone in missing matches due to suspension, with Cristian Romero and Destiny Udogie also seeing red this term. “Really pleased to get Biss back. He is such an important part of our set-up with the way he plays in that role,” Postecoglou said. “If you look at the first third of the season, from a results perspective I reckon we are still on the positive side of the ledger. “Performance-wise, I still think we are on the positive side of the ledger, even though we’ve had some disappointments, but an area we need to improve is discipline. He is part of that. “That has let us down in this first half of the year. Not just in terms of cards, but being really focused in our approach and these are the things we need to learn as a team. “I am sure Biss probably feels himself a bit frustrated with the fact he had such a great start and now it’s been disrupted, but great to have him back. Particularly against a team like City, he is going to be really important for us. “It is kind of a lesson for him and us as a group. If you want things to run a bit more smoothly, you have to be really disciplined in your approach and really focused in what you do. “Hopefully he comes out of this knowing for him to maintain becoming a really important part of our team, he needs to have that discipline and focus.” The return of Bissouma is welcome for Postecoglou, who remains without Pape Sarr (hamstring) and this week discovered Rodrigo Bentancur (ankle) will be out until February Spurs’ list of absentees has now reached double figures, which contributes towards the visitors being long odds to upset City on Sunday. Nevertheless, Tottenham boast an excellent record against the Premier League champions, albeit previously playing in a pragmatic way, and Postecoglou knows his markedly different attacking approach will bring questions. He added: “That’s not a bad thing. That’s a good thing. We need to be scrutinised. I need to be scrutinised, I need to be questioned. That’s what tests my resolve. “I ain’t gong to change, but bring it on. It doesn’t just test me, it tests the players, it tests the club. How resolved are we about doing this? “Look at all the top teams, they’ve all been through the process, through the tough times. They’ve all got questioned, they’ve all got scrutinised, they’ve all had criticism. “How did they handle it, the ones that are through the other side? The ones who handled it differently, where are they now? I need to be scrutinised, I need to be questioned. That's what tests my resolve Ange Postecoglou “I have a real strong belief in what I do and where the team is heading and I’m just not going to waver from it. “There’s a reason I’m sitting here and the reason is the end game is not to beat City. If that’s the end game, that’s been done. “It’s a hell of an achievement to knock them off, absolutely, but it’s not why I’m here. “I’m trying to set up a team to be successful.” Read More Police charge more than 40 away fans after major disorder outside Villa Park Pep Guardiola: Spurs under Ange Postecoglou an ‘incredible advert’ for football ‘We never lost trust’: Sarina Wiegman remained confident of England comeback Erik ten Hag backs under-fire Manchester United goalkeeper Andre Onana Mauricio Pochettino understands reason behind early struggles for Moises Caicedo Ange Postecoglou knows he can succeed at Tottenham by sticking to plan