Putting together a dating app bio is a real challenge. First, it needs to authentically

Justin Thomas committed to a driver change, tinkered a little with his swing and got immediate results with a 5-under 67 that left him four strokes off the pace Friday in the Fortinet Championship

SAN FRANCISCO--(BUSINESS WIRE)--Oct 5, 2023--

Holiday Inn-owner IHG posted a rise in quarterly revenue per room on Friday on higher room prices and

A former member of BA's cabin crew tells her story of being used as a "human shield".

Scientists have grown human kidneys in pigs, for the very first time. Researchers at the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences and Wuyi University created human-pig chimeric embryos containing a combination of human and pig cells. When they transferred into 13 surrogate pig mothers, they developed kidneys that contained mostly human cells at a rate of 50 to 60 per cent, giving hope for potential transplants in the future. “Rat organs have been produced in mice, and mouse organs have been produced in rats, but previous attempts to grow human organs in pigs have not succeeded,” said the senior author Liangxue Lai. “Our approach improves the integration of human cells into recipient tissues and allows us to grow human organs in pigs.” The kidneys were not entirely human as they included vasculature and nerves made mostly from pig cells, meaning they could not be used for transplantation in their current form, but it is still a pretty impressive step. And apart from the kidneys, the embryos were dominated by pig cells, with very few human cells in the brain or central nervous system. Making brains using human and pig cells is very controversial for ethical reasons, so there are tight regulations for this kind of research. Meanwhile, pig cells tend to outcompete human cells during development, so previous experiments have created embryos that are almost entirely pig. The latest work, published in Cell Stem Cell, overcame this by genetically engineering a single-cell pig embryo so that it lacked two genes needed for kidney development. This created a gap within the embryo that could be filled by human cells. “We found that if you create a niche in the pig embryo, then the human cells naturally go into these spaces,” said Prof Zhen Dai of Guangzhou Institutes of Biomedicine and Health, another senior author. The scientists said that being able to incubate a fully human kidney inside a pig would be likely to take many years. “We would probably need to engineer the pigs in a much more complex way and that also brings some additional challenges,” said Miguel Esteban, also of the Guangzhou institute and a senior author. A central challenge would be to allow human nerves and vasculature to develop within the target organ without nerve cells developing in the central nervous system that could lead to a humanised brain. “Even theoretically it’s not clear how you’d do that,” said Ilic. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

An $835 million Powerball jackpot is up for grabs if players are willing to brave incredibly long odds

GOTHENBURG, Sweden--(BUSINESS WIRE)--Jun 19, 2023--

Crystal Palace manager Roy Hodgson hailed Joachim Andersen’s “colossus” performance after the Dane’s late equaliser secured a 1-1 draw against Brentford at the Gtech Community Stadium. Kevin Schade’s stunning opener was cancelled out by Andersen in the 76th minute as both Brentford and Palace shared the spoils for a fifth consecutive time in the Premier League. Hodgson lauded the centre-back’s overall performance which nullified the threat of Brentford duo Yoane Wissa and Bryan Mbeumo, who both fired blanks for the first time this season. “I thought Joachim Andersen was the outstanding player today in our team and maybe the outstanding player on the field,” Hodgson said. “I thought he was a colossus today, he won every header in both ends of the field and I thought he won every challenge he went into, he was a leader figure and he drove the team forward. “He wasn’t afraid to come more than midway into the opponent’s half as we saw and he was playing balls and spraying it around from about 25 yards from goal and that was a great responsibility that he took there. “I think it was very fitting that he got the goal even though it wasn’t a classic.” For the first time this season Brentford appeared lost without focal point Ivan Toney, who is suspended, as they struggled to look threatening in the final third. Frank highlighted his frustration at his side’s attacking performance and credited Hodgson’s Palace for their defensive efforts. “No ( I wasn’t happy with the amount of Brentford chances) but I am not surprised,” Frank added. “For whatever reason and I can’t figure it out, the two teams (Brentford and Palace) cancel each other out more or less in these games. “In five games we’ve played them the amount of chances the two sides have created are very limited and I would have loved to have taken more. “I think in the half opening transitions we lacked the final pass action to create more and we should’ve won 1-0 which is so frustrating.” Schade’s 18th-minute goal was his first for Brentford since his switch in January and Frank talked up the winger’s qualities. “I am so pleased for him, it’s so important for the confidence and what a goal it was,” Frank said. “I loved his initiative to run at the opponent where he got all the way into the box and was composed before a fantastic finish so hopefully he can do more of those nice goals.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live How England’s players rated during Twickenham defeat to Fiji Tottenham boss Ange Postecoglou toasts as early birthday present Liverpool lucky with availability of centre-backs this season – Jurgen Klopp

Ange Postecoglou is close to being appointed the new Tottenham manager after winning a domestic treble with

Carlos Vela scored an injury-time penalty as Los Angeles FC surged to the top spot in Major League Soccer's Western Conference on Saturday, and Cincinnati maintained their charge at...

Decked out in friendship bracelets and glitter, fans lined up ahead of the first Argentina show of Taylor Swift's "Eras Tour" Thursday ready to shake off the bad blood of the upcoming presidential election -- until they were met...