There are still more questions than answers about what led up to one of the worst shipwrecks in recent Mediterranean history, in which some 500 people are feared dead

Saturday's roundup of transfer rumours includes news on David de Gea's uncertain Man Utd future, Arsenal's pursuit of Chelsea's Kai Havertz being complicated by Bayern Munich, Real Madrid's interest in Kylian Mbappe and more.

Does very hot weather leave you feeling more exhausted and lethargic than usual? There might be an initial surge of joy when the sun finally comes out – but once temperatures really creep up, we can end up feeling physically drained, wondering whether we should follow the Mediterranean’s lead and start introducing daily siestas. So, why does hot weather make us so tired? We asked a doctor to explain… Our bodies have to work harder in the heat “When the weather is hot, our bodies have to work harder to cool themselves down,” says Dr Zulqarnain Shah, medical director at SSP Health and GP at SSP Health practice Colne Road Surgery. “The body’s natural cooling mechanism involves increasing blood circulation near the skin’s surface and promoting sweat production. These physiological changes can lead to fatigue and a feeling of lethargy. It is essential to recognise that this fatigue is a normal response to heat and is typically temporary.” Dehydration Low energy and tiredness are also common when you’re lacking hydration. “Hot weather increases the rate of fluid loss through sweating, leading to dehydration. Dehydration can contribute to fatigue and make you feel even more lethargic,” adds Dr Shah. “To avoid this, it’s important to stay adequately hydrated by drinking plenty of fluids, especially water. Aim to drink even when you’re not feeling thirsty, as thirst is not always an accurate indicator of dehydration.” Heat exhaustion “Prolonged exposure to heat can result in heat exhaustion, a condition characterised by symptoms such as heavy sweating, weakness, dizziness, nausea, headache, and muscle cramps. If you experience these warning signs, it’s crucial to move to a cooler environment, drink fluids, and rest. If symptoms persist or worsen, seek medical attention promptly,” says Shah. It’s important to pay attention to warning signs, as if heat stroke develops, this is a medical emergency. Shah stresses: “Heat stroke is a severe and potentially life-threatening condition that requires immediate medical intervention. It occurs when the body’s temperature regulation fails, and the core temperature rises dangerously high. “Symptoms may include a high body temperature (above 39.4C), altered mental state, confusion, rapid breathing, rapid heartbeat, and even loss of consciousness. If you suspect heat stroke, call emergency services immediately.” Sleep deprivation The extra tiredness could also be linked to poor sleep, as this can really suffer in the heat. “Hot temperatures can disrupt sleep and lead to poor sleep quality. The body needs to cool down to initiate sleep, and the excessive heat can make it difficult to reach the optimal sleep temperature,” explains Shah. “To improve sleep in hot weather, consider using fans or air conditioning, wearing lightweight and breathable sleepwear, keeping your bedroom well-ventilated, and using lighter bedding.” Pre-existing conditions could get worse Many people living with chronic or long-term health conditions deal with fatigue, which may flare up during heatwaves. “Hot weather can exacerbate symptoms and increase fatigue in individuals with certain chronic health conditions. Conditions such as heart disease, kidney problems, and respiratory issues can be particularly sensitive to heat,” notes Shah. “It’s vital to be aware of your specific health condition and consult with your healthcare provider for personalised advice on managing your symptoms during hot weather. They may recommend staying in cooler environments, adjusting medications, or monitoring your fluid intake more closely.” Read More Airbnb customer furious after being charged extra over dog hair People seek hay fever advice once every three seconds, says NHS England Why is my hay fever so bad at the moment? How to tell if you have Covid or heatstroke Why do heatwaves in the UK feel hotter than abroad?

Despite the lack of sufficient support in Congress to pass a new assault weapons ban, President Joe Biden on Friday said the US has “reached a tipping point” in the fight to strengthen America’s gun laws, due to the activism of the gun violence prevention movement that has gathered increasing strength in recent years. Mr Biden, who was delivering remarks at the National Safer Communities Summit in Hartford, Connecticut, at the invitation of Senator Chris Murphy and a coalition of gun safety groups including Everytown, Moms Demand Action and Giffords, recounted some of the more than 20 executive actions his administration has taken to stem the tide of mass shootings since he took office. He said those politicians who claim to be concerned about crime should realise that crime can’t be tackled without dealing with gun violence. “It’s a simple proposition,” he said. The president also lamented how since 2020, firearms have been the leading cause of death for children in the United States — more than automobile accidents or cancer. He recalled how the assault weapons ban he wrote into the 1994 crime bill enacted under then-president Bill Clinton cut mass shootings “significantly” only to see their number triple when Mr Clinton’s successor, George W Bush, allowed the ban to expire with the aid of a Republican Congress, allowing military-style rifles and high-capacity magazines to “come back into vogue”. Mr Biden also called for a repeal of the Protection of Lawful Commerce in Arms Act, which immunises gun manufacturers from lawsuits filed by gun violence victims, and for the enactment of universal background checks before anyone can purchase high-powered rifles, many of which are modelled off of those issued to American soldiers, as well as safe storage requirements for such weapons. “The United States of America has the finest fighting force in the history of the world [and] provides … service members with the most lethal weapons on Earth. We also require them to receive significant training before they’re allowed to use them. We require extensive background checks and mental health assessment that before they can … use them [and] require them to lock them up or store the weapon responsibly,” he said. “Every gun owner should be required to have the same requirements held to him or her,” he added. The president also hailed governors who have taken action to strengthen state gun laws, including Connecticut’s Ned Lamont, who recently signed more than 12 separate bills to strengthen his state’s firearm regulations, and praised state governments in Illinois and Washington for passing assault weapon and ghost gun bans, as well as the 21 states that have enacted so-called “red flag” laws to allow courts to temporarily disarm people who are determined to pose a risk to the community by a judge. Though chances of a federal assault weapons ban making it to his desk are slim to none given the composition of Congress, Mr Biden promised the gun safety advocates that he will “never stop fighting”. “We will ban assault weapons in this country … we will hold gun makers liable, we will beat the gun industry,” he said. Read More Fox News producer behind chyron calling Biden a ‘wannabe dictator’ parts ways with network Biden snaps back as reporter asks him about ‘big guy’ controversy Biden, looking to shore up Hispanic support, faces pressure to get 2024 outreach details right

MrBeast has reportedly brought participants from all over the world to take part in an Olympic-style sporting event

Jack Grealish recently made headlines with his wild celebrations after winning the treble with Manchester City and now an iconic photo from this time has been hung up in the Louvre... well, kind of. The footballer shared a photo of himself celebrating with players as they toured Manchester in an open-top bus parade. In the photo, Grealish can be seen topless with his eyes closed and arms stretched out, taking in the euphoric atmosphere. Sign up to our free Indy100 weekly newsletter Clearly, the 27-year-old is a fan of the snap as he shared it on Twitter and declared: "Hang it in the Loooouvre," with a blue heart and laughing emoji. Grealish's spelling of the famous museum in Paris is in reference to team-mate Erling Haaland's entertaining (and uncanny) impression of John Stones who has got a Yorkshire accent. Now, it looks like Grealish's wish has come true thanks to Paddy Power as they went to the French capital to put the photo up in the Louvre, where the famous Mona Lisa is also on display. However, they were ultimately told by confused staff members that their unusual request was not possible. So it was time to decide to think outside the box, and Grealish didn't technically say exactly where in the Louvre the photo should be hung, right? Instead, the bookmakers were able to put the photo up somewhere else inside the Louvre - or Loo-vre as they put it on display inside the museum toilets. The stunt clearly amused City fans who praised Paddy Power's commitment to the bit. Elsewhere, Ruben Dias threw up in Jack Grealish's mum's handbag during Man City's boozy celebrations and Troy Hawke reconciles with a very drunk Jack Grealish at Man City's open-top bus parade. Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

Although Michael Cera and Aubrey Plaza's wedding didn't seem to work out, the 'Barbie' star is all praises for his ex-girlfriend

One of the scientists whose work pioneered the development of medications such as Ozempic and Wegovy has revealed why life may become “so miserably boring” after two years of using the drug. Ozempic is an FDA-approved medication used for the treatment of type 2 diabetes. It works by mimicking a hormone called glucagon-like peptide 1 (GLP-1), which regulates blood sugar levels and slows down the rate at which food leaves the stomach, often creating the feeling of fullness. These semaglutide injections – sold under the brand names Ozempic and Wegovy – have soared in popularity as many people, including Hollywood celebrities, have used it for weight loss. What’s more, people have also found Ozempic has been effective in curing their addictive habits, like drinking, smoking, shopping, or nail biting. However, because of Ozempic’s increasing popularity, it has led to national shortages of the type 2 diabetes treatment – leaving those who actually need it without. In an interview with Wired, professor Jens Juul Holst – who received the Warren Alpert Foundation Prize in 2021 for his work developing treatments based on the GLP-1 hormone – spoke about the effects of Ozempic, and why he believes many people will stop taking the medication after just a few years. “What happens is that you lose your appetite and also the pleasure of eating, and so I think there’s a price to be paid when you do that,” Holst told Wired. “If you like food, then that pleasure is gone. The craving for food for some people is taken away when they take GLP-1 drugs.” He continued: “That may eventually be a problem, that once you’ve been on this for a year or two, life is so miserably boring that you can’t stand it any longer and you have to go back to your old life.” Holst added that medications like Ozempic and Wegovy have been on the market since 2005, though studies show that these people don’t stay on them for very long. “It’s just like every other drug, they don’t stay on it for many reasons,” he explained. “One of the reasons, as I said, is that once you have tried it and you realise you’ve lost interest in food, then that may be enough.” “We don’t know why people stop taking these drugs, but we know for a fact that they do stop. They do that all over the world.” A 2020 study found that 70 per cent of people who took GLP-1 drugs for type 2 diabetes stopped taking them within two years. However, this could pose a problem for many patients taking semaglutide injections. Research has found that people who stopped taking Ozempic or Wegovy for weight loss experienced weight rebound. A trial published in April 2022 saw participants gain back two thirds of the weight they had lost after 68 weeks of taking semaglutide. As for celebrities who use the once-weekly injection for weight loss, despite not having diabetes or clinical obesity, Hans instead called attention to the “many terrible problems” that those with diabetes have struggled with by not having drugs like Ozempic readily available. “Have you ever visited a diabetes hospital? It’s really deplorable,” he said. “People come in with amputated limbs and compromised cognitive functions and heart problems or they can barely move – they’re miserable and depressed. It’s really serious. There is so much you can improve with a drug that is not only a weight-loss drug but is also an anti-diabetic.” Amidst the popularity of semaglutide injections, the US Food and Drug Administration has issued warnings for consumers not to use off-brand versions of Ozempic or Wegovy, because they may not include the same GLP-1 hormone used in approved medications. Earlier this month, agency officials reported problems with patients using compounded versions of semaglutide – which combines traditional semaglutide with other ingredients. These drugs are not FDA-approved, and the agency does not verify the safety or effectiveness of compounded drugs. Consumers should only use drugs containing semaglutide with a prescription from a licensed health care provider and obtained from a state-licensed pharmacy or other facilities registered with the FDA, the agency said. Read More What is ‘Ozempic face’? Doctors warn about facial ageing side effect of diabetes medications How does Wegovy work? The ‘game changing’ weight loss drug beloved by Hollywood FDA warns against using off-brand versions of Ozempic, Wegovy for weight loss Scientist behind Ozempic says drug can make life ‘so miserably boring’ Pregnant Stassi Schroeder admits she wants to ‘try’ Ozempic after giving birth Doctors warn about ‘Ozempic face’ side effect of medications

Bangladesh crushed Afghanistan by 546 Saturday to secure the biggest Test victory margin by runs in nearly 90 years after Taskin Ahmed saw off the...

Tom Cruise and Cameron Diaz denied romantic rumors while praising each other's professionalism and talents in the past

'I'm just diversifying, and that this is just how it's going to be,' the streamer explained, debunking the notion that he was 'upset' with Twitch

Alison Goldfrapp has shared her experiences of working with Tricky and Bryan Ferry.