Could bats hold the secret to beating Covid and cancer?
Bats could hold the key to unlocking new ways to combat cancer, a new study suggests. A paper published by Oxford University Press, looks at the rapid evolution of bats for their abilities to both host and survive infections such as Covid-19 as well as cancer. The animals are known to have a strong immune system which helps fight off many viruses and diseases. These mammals are also thought to have played a role in the emergence of Covid-19 and scientists say such characteristics are interesting to investigate due to the implications it might have on human health. According to the research, understanding the mechanisms of the bat’s immune system that allows these animals to fight off viral infections – may pave the way to understanding how to prevent disease outbreaks from animals to people. To conduct the study, researchers sequenced the genomes of two bat species - the Jamaican fruit bat and the Mesoamerican mustached bat. The team used advanced technology from Oxford Nanopore Technologies and bat samples collected by the American Museum of Natural History in Belize. They then compared the bat genomes to those of other mammals. The results revealed that bats possessed genetic adaptations in proteins which are related to DNA repair and cancer suppression. It was found that bats had adaptations in six DNA repair-related proteins and 46 cancer-related proteins. The study also found that bats had more than double the number of altered cancer-related genes compared to other mammals, which provided further evidence that they have the ability to suppress cancer. “By generating these new bat genomes and comparing them to other mammals we continue to find extraordinary new adaptations in antiviral and anticancer genes,” said the paper’s lead author, Armin Scheben. “These investigations are the first step towards translating research on the unique biology of bats into insights relevant to understanding and treating ageing and diseases, such as cancer, in humans.” The results open up new paths for understanding and studying the links between cancer and immunity, which offers hope that these insights from bats might possibly lead to new treatments for human illnesses. According to the United States Department of the Interior, there are over 1,400 species of bats worldwide and are mostly found in extreme deserts and polar regions. In the US and Canada, there are about 45 species of bats. Read More British bats ‘can help identify coronaviruses with potential to infect humans’ Coronavirus origins still a mystery 3 years into pandemic Groundbreaking migraine treatment offers ‘new hope’ for patients World Sepsis Day: What is the condition and its symptoms? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis
2023-09-20 22:28
There's too much guesswork in renting an Airbnb. The short-term rental giant is trying to fix that
Airbnb says the biggest reason it loses some bookings to hotels is that people never know exactly what their Airbnb rental will look like until they check in
2023-11-08 21:26
Liverpool held to 2-2 draw at Brighton in another setback for Jurgen Klopp's team
Brighton and Liverpool traded defensive mistakes before settling for a 2-2 draw in the Premier League in another setback for Jurgen Klopp’s team
2023-10-08 23:20
Ford getting complaints about "ear piercing" noise from speakers in F-150 trucks
Ford has gotten about 100 complaints from F-150 truck owners who say the speakers in their vehicles are emitting a loud, annoying noise that sounds like static, or glass shattering, and which cannot be shut off.
2023-08-25 02:25
Who was Javonnta Murphy? Man found in barrel at Malibu Lagoon identified as aspiring rap artist
Murphy was found stuffed in a 55-gallon drum, which was spotted floating along the coast near the 23200 block of Pacific Coast Highway on July 30
2023-08-03 16:56
What is sleep apnea and how is Joe Biden treating his using a CPAP machine?
Joe Biden recently began using a CPAP machine to treat sleep apnea, the White House announced on Wednesday, after observers noticed mask marks on the president’s face. “Since 2008, the president has disclosed his history with sleep apnea in thorough medical reports. He used a CPAP machine last night, which is common for people with that history,” White House spokesman Andrew Bates said, CNN reports. Here’s what you need to know about the president’s diagnosis, and how he is treating his sleep apnea. What is sleep apnea? Sleep apnea is a common condition in which one’s breathing repeatedly stops and starts during sleep. According to the Mayo Clinic, it is commonly caused by the relaxation of throat muscles, blocking the flow of air. Less frequently, sleep apnea is the result of the brain not sending the proper signals to the respiratory system. Symptoms of sleep apnea include loud snoring, episodes of breathing stopping during sleep, and gasping for air. Those with high weight, large neck circumference, and a family history of the condition are considered at greater risk of getting sleep apnea. Men are two to three times more likely to have sleep apnea. About 30 million people in the US have the condition, though far fewer, roughly six million, are diagnosed as such, according to the American Medical Association. Sleep apnea can contribute to fatigue, circulatory issues, and diabetes in those who have it. What is a CPAP machine? CPAP stands for continuous positive airway pressure machine, and the device is one of the most common treatments for sleep apnea, according to the Cleveland Clinic. CPAP machines help keep a patient’s airways open by delivering air through tubes into a mask that’s worn during sleep. How long has President Biden had sleep apnea? Mr Biden first disclosed that he had experienced sleep apnea in 2008 medical disclosures, though more recent medical evaluations have not listed it as a cause for serious concern. A 2019 evaluation disclosed that Mr Biden’s sleep apnea had “has been considered, but his symptoms have improved significantly” following sinus and nasal passage surgeries, according to CNN. A White House physical two years later listed Mr Biden’s throat clearing and coughing during speeches as areas of “observation.” His most recent such evaluation didn’t mention sleep apnea. As The Independent has reported, Mr Biden at age 80 is the oldest president in US history. His health condition, and that of other senior US politicians, has alarmed some observers. Read More White House reveals Biden uses CPAP machine for sleep apnea after president seen with marks on his face Parents awarded $15m after son with dwarfism dies in Boston hospital sleep study Should I see a doctor about my bad sleep? Dennis Rodman responds to critics after he wore skirt to Pride parade Dwyane Wade recalls daughter Zaya being ‘scared’ and hiding from him after coming out Chrissy Teigen and John Legend welcome fourth child via surrogate: ‘Our new love’
2023-06-29 08:59
Love says he got text from Rodgers before opening 1st training camp as Packers' starting QB
Jordan Love received some advice from his four-time MVP predecessor the night before his first training camp workout as the Green Bay Packers' starting quarterback
2023-07-27 08:46
Tesla’s profits dip as Elon Musk goes on rant against staff working from home
Electric car maker Tesla’s profits took a dive in the third quarter, according to an earnings call on Wednesday in which the company’s chief Elon Musk blamed staff working from home for being “detached from reality”. Tesla’s profits in Q3 of 2023 have plunged by over 40 per cent compared to the gains it made in the same period last year after the company slashed its car prices by around 25 per cent in an attempt to compete with other EV makers. The EV manufacturer reported a net profit of about $1.9bn for the time between July through September, which is a 44 percent drop from the $3.3bn it made in the same three-month period last year. While the company has seen a small increase in overall revenue of about $23bn from the $21bn the same time last year, the figures are still lower than Wall Street expectations. Mr Musk also dampened hopes of the company’s anticipated Cybertruck reviving profits in the near future, announcing that it would take at least 18 months for the truck to become profitable as it could go on sale only by the end of November. “There will be enormous challenges in reaching volume production with Cybertruck and making the Cybertruck cash flow positive,” the Tesla titan told investors and analysts in the earnings call. “The blood, sweat and tears that will be required to achieve that is just staggering,” he added. Over the last year, Tesla has slashed the prices of its cars by quarter to boost sales. Growing competition with the introduction of EVs by other car makers in the US, including BMW, Toyota, Mercedes, GM and Hyundai, has also coincided with Tesla’s share of vehicles in the EV market reducing in the last quarter. In the earnings call, Mr Musk also said staff working from home are taking advantage of those who cannot work from home. “Like... what about all the people that have to come to the factory and build the cars?” he asked. “Why did I sleep in the factory so many times? Because it mattered,” the Tesla chief said. Mr Musk echoed the statements he made in an interview with CNN earlier this year in which he called remote work “morally wrong”, arguing that it is unfair to those who cannot have the option. “Get off the goddamn moral high horse with the work-from-home bullshit,” he said. Tesla also pointed fingers at its reduction in production while it upgraded its factories as one of the factors behind the profit slump. It said it has also been making big investments in AI and “commissioned one of the world’s largest supercomputers.” “We have more than doubled the size of our AI training compute, accommodating for both our growing data set & Optimus, which is currently being trained for simple tasks through AI rather than hardcoded software, while its hardware continues to improve,” Tesla said. But all is not gloomy as the company says the first deliveries of its Cybertruck are scheduled for 30 November and Tesla’s Model Y remains the “best-selling vehicle of any kind” in Europe. Read More X begins charging new users to post as part of trial EU asks Elon Musk to ‘walk the talk’ on X/Twitter disinformation over Hamas attack AOC wants to ‘trade in’ her Tesla for union-made electric vehicle amid historic auto workers strike Amazon to start dropping packages into people’s gardens using drones in the UK Facebook has stopped working Facial recognition firm Clearview AI overturns UK data privacy fine
2023-10-19 14:18
Alcaraz, Djokovic take centre stage at Wimbledon
Carlos Alcaraz and Novak Djokovic can take a step closer to a Wimbledon title showdown on Friday as Andy Murray resumes his big-hitting duel with Stefanos Tsitsipas...
2023-07-07 20:55
Kentucky Democrat Beshear links GOP challenger to reality of abortion law in reelection campaign
Democratic Gov. Andy Beshear has pushed his opposition to Kentucky’s abortion ban to the forefront of his reelection campaign
2023-09-06 12:57
Chelsea detail Romeo Lavia plan after completing £58m deal
Chelsea have completed the signing of midfielder Romeo Lavia from Southampton for a reported £53million, possibly rising to £58m, taking their total number of first-team acquisitions this summer to eight. The 19-year-old, who has played just 29 times in the Premier League, has signed a seven-year deal having made clear earlier this week his desire to move to Stamford Bridge over Liverpool, who also had a bid accepted. Chelsea have now spent more than £350m during this transfer window once performance-related add-ons are taken into account, though that has been significantly offset by fees received for player sales. Lavia told the club’s website: “I can’t wait to meet all my new team-mates and build a chemistry together to achieve great things together.” Lavia, who made his Belgium debut in a friendly win against Germany in March, will likely compete with Enzo Fernandez and fellow new-signing Moises Caicedo - the two most expensive players in English transfer history - for a starting place in Mauricio Pochettino’s midfield. Chelsea broke that record for the second time in eight months on Monday with the capture of Caicedo from Brighton for an initial £100m, possibly rising to £115, eclipsing the £106m they paid Benfica for Fernandez in January. Co-sporting directors Laurence Stewart and Paul Winstanley said: “We are very pleased to welcome Romeo to Chelsea. “He demonstrated his quality in the Premier League last season at Southampton, showing maturity despite his young age, and is a player we have monitored for some time. “We believe he is ready to make an impact at Chelsea throughout the current campaign, and in the coming years.” It is also understood that a deal is yet to be agreed with Newcastle for defender Lewis Hall, though a move for the 18-year-old is close. Hall signed a new six-year contract with the club just days ago and was set to spent the season on loan at Crystal Palace but Newcastle’s offer, believed to be £28m, has persuaded the club to reconsider. As an academy product, any sale would be recorded as pure profit in Chelsea’s books as they look to remain within Financial Fair Play rules following a total transfer outlay over the last year in excess of £900m. A deal had also been agreed with Palace for the transfer of winger Michael Olise after the club met his £35m release clause, but the France Under-21 international has opted to remain at Selhurst Park and signed a new four-year contact on Thursday. PA
2023-08-18 19:46
Kyle Bradish solid for AL-best Orioles, who beat Red Sox 11-2 to run win streak to 6 games
Kyle Bradish struck out nine batters in six strong innings, Adley Rutschman homered and drove in three runs, and the AL-best Baltimore Orioles beat the fading Boston Red Sox 11-2
2023-09-09 10:57
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