By Maggie Fick LONDON Soaring U.S. demand for Novo Nordisk's weight-loss drug has reduced the pressure from investors

The names of the three US marines killed in a horrific plane crash in Australia's Top End have been released

Paul George scored 27 points, Russell Westbrook added 18 and the Los Angeles Clippers beat the Orlando Magic 118-102 as future teammate James Harden watched from a suite

England host Australia in a sold-out friendly at Wembley on Friday evening. Here, the PA news agency takes a look at five of the main talking points ahead of the international encounter. Some Ashes revenge for England? There is a long sporting rivalry between these countries and revenge would be sweet after an epic Ashes summer ended with the urn returning Down Under. Jonny Bairstow’s controversial stumping by Alex Carey particularly stuck in the craw during a dramatic 2-2 series draw that saw emotions run high. England have the chance to exact a slither of revenge under the arch on Friday, when Gareth Southgate expects the sporting rivalry to “add an extra edge” to the occasion. …or will there be a famous second Socceroos win? This will be the first time these nations have met at Wembley, with the only previous two encounters on English soil played at the Stadium of Light and Upton Park. Wayne Rooney made his debut in the latter friendly in February 2003, but it was Australia that won 3-1 on the night. It is the only time England have lost in seven meetings with the Socceroos and Graham Arnold’s side, ranked 27th in the world, would love nothing more than to repeat the feat on Friday. A chance to experiment for Southgate Last month’s friendly against Scotland ended a run of 16 successive competitive matches for England, covering last year’s Nations League campaign, the 2022 World Cup and Euro 2024 qualification. Southgate said before the game that over-experimenting at Hampden Park would be “ridiculous” but still managed to try a few things as his side ran out 3-1 victors. Lewis Dunk made his second international start – five years after his first – in central defence alongside Marc Guehi, while Aaron Ramsdale got the nod in goal. Southgate will be tempted to look at several areas of the squad again this time, including uncapped Levi Colwill at left-back, returning Jarrod Bowen in attack and Trent Alexander-Arnold in midfield. Can Watkins or Nketiah stake claim to be Kane deputy? Harry Kane’s goalscoring feats are as impressive as they are well documented. Already the highest scoring man in England’s history, he will match Sir Bobby Charlton’s 23-goal international haul at Wembley if he scores against Australia. But Southgate may well be tempted to try a different striker given their inability to find a reliable back-up to the Bayern Munich player. Callum Wilson fulfilled the role in Qatar but is injured this time around, with in-form Aston Villa striker Ollie Watkins receiving his first call-up since March 2022. Uncapped Arsenal striker Eddie Nketiah, England Under-21s’ all-time top scorer, is another man looking to push his claim to be Kane’s deputy ahead of the Euros. Israel-Palestine victims to be remembered Black armbands will be worn and a period of silence observed before Friday’s friendly to remember the innocent victims of the conflict in Israel and Palestine. The Football Association has confirmed its plans to pay tribute, having come under pressure to illuminate the Wembley arch in the colours of the Israeli flag following attacks by Hamas militants over the weekend which were followed by Israeli bombardment of the Gaza Strip. Flags, replica kits and other representations of nationality not linked to England or Australia will not be permitted inside Wembley. Read More FA criticised for ‘weak response’ to Israel and Palestine conflict Sebastian Korda defeats Ben Shelton to book first ATP 1000 semi-final in Shanghai 5 talking points as Republic of Ireland seek strong end to Euro 2024 qualifying Abbas Miski: Huge honour to be first Lebanese player to feature in Grand Final Sam Tomkins to haunt his former side? – Super League Grand Final talking points Stephen Kenny: Republic of Ireland must still believe in Euro 2024 qualification

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Watch a live view of St Peter’s Square in Vatican City, as temperatures reach 38C. Sizzling temperatures have swept across Europe in recent days, and the heatwave has taken hold across many popular holiday hotspots in the Mediterranean, such as Spain, Italy and Greece. Much of southern Europe has been in the high 30s, while some parts of southern Italy and areas in Greece have been in the low-to-mid 40s, which is eight to 12 degrees above the seasonal average for the region. The hottest temperature recorded was around 45C and the heatwave has caused health issues, leading to a strain on local medical services during a busy tourist period. Fifteen cities in Italy, most of them in the country’s centre and south, were under heat advisories due to a high level of risk for older adults, children and other vulnerable people. Last week, a 44-year-old man, who was painting a zebra crossing in 40C heat in the northern town of Lodi, lost consciousness and later died in hospital, local media reported. Read More The pope's Ukraine peace envoy heads to Washington with the plight of children top of his agenda The Vatican's next doctrinal guardian defends the book on kissing he wrote as a young priest A wave of political turbulence is rolling through Guatemala and other Central American countries

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