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What Charles Leclerc needs to finally claim victory from pole in first Las Vegas Grand Prix
Amid the maelstrom swirling on the other side of the Ferrari garage in the last few days at the Las Vegas Grand Prix, Charles Leclerc has been razor-sharp. Fastest in the sole practice session on Friday, the Monegasque is so often ice-cool on the tight, twisty street circuits that so regularly crop up now in Formula 1. Such was his confidence – and previous qualifying form in similar conditions – Leclerc was actually favourite with the bookies for pole position ahead of Max Verstappen. The Ferrari man proved them right, sealing a Ferrari one-two with Carlos Sainz qualifying in second. Unfortunately however, the Spaniard will not be starting alongside his team-mate for the inaugural Saturday night race. Sainz’s ridiculous 10-place grid penalty for exceeding his gearbox allocation – which only came about due to the FIA’s incompetence after manhole-gate on opening night – has wiped out Leclerc’s most helpful aid to win the 50-lap race. For those desperate for an engrossing battle at the front, not least F1 and LVGP chiefs, it is a bitter blow. Leclerc will have to break an unwelcome streak, too. Since his last win 16 months ago in Austria, the 26-year-old has been on pole position eight times. Rather excruciatingly, six of those eight have still resulted in podiums. Ferrari’s race-pace has been their Achilles’ heel but Leclerc is optimistic after Sainz was victorious on a similar track layout in Singapore in September. “The race is where we lack performance so I hope we can put it all together,” he said post-qualifying. “We know that Red Bull are going to be very strong, but we’ve had positive signs on the high fuel [in practice] – hopefully we can convert that pole position to a win. “I think we are closer [to Max] than other races. If there’s one race to win [this year] other than Singapore, it’s this one.” Leclerc will need two things that have deserted him in order to taste victory in Nevada tomorrow: a peerless strategy and just a bit of luck. From lights out, Leclerc must get off to an exemplary start, while hoping Verstappen – who compared the track to the National League after qualifying – on the dirtier side of the track falls back into the pack. Early on, staying outside the DRS window of Verstappen behind ahead of the Vegas strip section – now the second-longest straight on the calendar – is imperative. But Ferrari must be bold with their tactical calls from lights out. The Scuderia have hampered themselves since producing a title-winning car at the start of 2022 with daft decisions from the pit lane. In a battle between Ferrari strategists and their rivals at Red Bull, there has been no contest. It is unlikely, given Red Bull’s outstanding race pace and straight-line speed. But Verstappen’s day to forget in Singapore two months ago should give Leclerc and the rest of the pack hope, even if it is simply a glimpse of an opportunity. TOP-10 - LAS VEGAS GRAND PRIX QUALIFYING 1. Charles Leclerc 2. Max Verstappen 3. George Russell 4. Pierre Gasly 5. Alex Albon 6. Logan Sargeant 7. Valtteri Bottas 8. Kevin Magnussen 9. Fernando Alonso 10. Lewis Hamilton Earlier in the day, Formula 1 and Vegas GP management did their no reputation no good with a lengthy statement explaining Thursday night’s titanic mess, which saw ticket holders witness just eight minutes of cars on track. Perplexingly, in amongst 600 words, there was no apology and no refund offered; instead, a $200 voucher to use at the Las Vegas Grand Prix gift shop. After a jumbled-up order in the final practice session, there was a sense of mystique surrounding who was the quickest team around this 3.8-mile street circuit. A circuit which, despite this week’s shenanigans, looks absolutely stunning from the sky. Think Singapore and Jeddah on steroids. On the track, Lando Norris admitted this week he “did not mind” where his first win comes – but it won’t be this weekend. Both McLarens, surprisingly short of pace, were knocked out in Q1 – Norris will start tomorrow’s race in 15th, Oscar Piastri in 18th. A recovery drive will be in order on Saturday night. It was also another day to forget for Lewis Hamilton. The seven-time world champion failed to qualify for the final session and will start the Vegas race in 10th. Resigned to his fate afterwards, he simply stated to race engineer Peter Bonnington: “Couldn’t go faster mate.” But his team-mate George Russell could – the Brit will start behind the top-two in third tomorrow and will be looking to steal a march on Verstappen heading into turn one. Yet the standout team in Vegas qualifying was Williams, with Alex Albon starting fifth and rookie driver Logan Sargeant producing his best qualifying performance of the season for sixth. And with it, the American could well have sealed his 2024 seat. Read More Charles Leclerc lights up Las Vegas to claim pole position for Ferrari Verstappen criticises Vegas GP: ‘Monaco is Champions League, this is National League’ F1 Las Vegas Grand Prix LIVE: Qualifying times and results in Sin City ‘It happens’: F1 fail to apologise or issue refunds to Las Vegas fans When does the Las Vegas Grand Prix start and how can I watch? F1 grid: Starting positions for Las Vegas Grand Prix
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How did surgeons carry out Britain’s first womb transplant?
Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. Read More Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out
2023-08-23 07:16
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