Eli Lilly said on Friday it was extending the deadline for its tender offer for Point Biopharma shares

A 17-year-old boy reportedly carves the name "Julian" on an 8th Century temple in Nara, Japan.

Bank of Montreal posted a surprise drop in fiscal second-quarter profit as it set aside a larger provision

You’ve been through all of life's ups and downs together, spent countless nights sipping countless bottles of wine, and caught up on everything from your Renaissance concert to relationships to The White Lotus. Yep, we’re talking about your ride-or-die bestie — who might be the trickiest to buy gifts for. Whether your bestie has an upcoming birthday, engagement party, or job promotion or you just want to celebrate National Best Friends Day on June 8, we've got a best friends gift for you.

Check out the best audio settings for Fortnite OG, including how to turn on visual sound effects, to dominate both Battle Royale and Zero Build.

Michael Penix Jr. threw for 450 yards and matched his career-high with five touchdown passes, and No. 10 Washington overwhelmed Boise State in a 56-19 win in the teams' season opener

The two leaders also agree to take steps to tackle the flow of fentanyl into the US.

Manchester United look to capitalise on their narrow Premier League win to open the season and retain their perfect start when they travel to Tottenham. Raphael Varane’s strike was enough on Monday to secure a 1-0 win, despite Wolves wasting chances and being denied a penalty late on. Erik ten Hag will look to see more chemistry between Bruno Fernandes and Mason Mount, while Spurs boss Ange Postecoglu will be encouraged by his side’s display at Brentford. Without Harry Kane, the Australian will hope the likes of Son Heung-min, James Maddison and Richarlison lead this new era in north London. Here’s everything you need to know about the fixture: When is Tottenham vs Man Utd? Tottenham vs Man Utd is due to kick-off at 5.30pm on Saturday 19 August at Tottenham Hotspur Stadium in London. How can I watch it? Viewers in the United Kingdom can watch the match live on Sky Sports Main Event and Sky Sports Premier League, with coverage on the channels from 5pm. Subscribers can stream the game via the Sky Go app. Team news Christian Romero has recovered from a head injury, but Spurs will likely be without Bryan Gil (groin), Rodrigo Bentancur (knee), Ryan Sessegnon (hamstring), Fraser Forster (back) and Alfie Whiteman (ankle). Tanguy Ndombele could be overlooked once again too, although this looks like a tactical call from Postecoglu. Lisandro Martinez is a doubt with an ankle injury, meaning Victor Lindelof could step in for the Argentine. Rasmus Hojlund (back), Kobbie Mainoo (ankle), Tyrell Malacia (knee), Amad Diallo (knee) and Tom Heaton (calf) are all set to miss out here. But former Spurs man Christian Eriksen could factor into Ten Hag’s plans after the disjointed partnership of Mason Mount and Bruno Fernandes in midfield against Wolves. Predicted line-ups Tottenham XI: Vicario; Emerson, Romero, Van de Ven, Udogie; Bissouma, Skipp, Maddison; Kulusevski, Richarlison, Son. Man Utd XI: Onana; Wan-Bissaka, Varane, Martinez, Shaw; Fernandes, Casemiro, Eriksen; Antony, Rashford, Sancho. Odds Tottenham win 9/5 Draw 11/4 Man Utd win 13/10 Sign up to bet365 using The Independent’s unique bonus code by clicking here Prediction Look for goals here. Spurs 2-2 Man Utd Read More Welcome to the remodelling of Mason Mount Harry Maguire must ‘fight for his position’ after rejecting move away from Man Utd Mason Greenwood timeline: How the Manchester United star fell from grace Fulham vs Brentford LIVE: Latest Premier League updates Liverpool vs AFC Bournemouth LIVE: Latest Premier League updates Wolverhampton Wanderers vs Brighton & Hove Albion LIVE: Latest Premier League updates

Michigan police arrested a male suspect on Thursday who allegedly carried out a shooting across multiple locations in the town of Saline, including an assisted living home. Saline police vehicles were seen at a United Auto Workers hall, as well as at the Linden Square Assisted Living Center, Fox 2 Detroit reports. Two victims were taken to local hospitals in critical condition, according to Huron Valley Ambulance, WXYZ reports. “Saline Police responded to an active shooter situation at Linden Square Assisted Living Center. Additional details are forthcoming,” police wrote on Facebook. “City and school facilities went on a temporary lock down in response. At this time, it is believed there is no further threat to the community.” A local resident told Detroit News the shooting appeared to be a domestic incident between residents who live across from the assisted living centre. All residents of the facility are safe and accounted for, CBS News reports. City and state buildings in Saline went on temporary lockdown during the shooting. This is a breaking news story and will be updated with new information.

TL;DR: As of June 18, get a refurbished Apple iPad Mini 2 for only $106.99

Premier League chief executive Richard Masters is “not too concerned” for now about Saudi Arabia’s ascendancy in football as he reasoned it takes time to become a dominant force. Al Hilal submitted a world-record £259million offer for Paris St Germain forward Kylian Mbappe, who has 12 months left on his current deal and been given permission to speak to the Saudi club. Cristiano Ronaldo and Karim Benzema have already joined the country’s Pro League while Liverpool have agreed a deal with Al-Ettifaq – managed by Steven Gerrard – to sell their captain Jordan Henderson. “Something new is obviously happening,” Masters told BBC Sport. “The Saudi Pro League have stated they want to be a top 10 league by 2030. “They are investing in players and managers to try to raise the profile of the league and clubs. “It has taken us 30 years to get to the position that we have in terms of profile, competitiveness and the revenue streams that we have. “I wouldn’t be too concerned at the moment but, obviously, Saudi Arabian clubs have as much right to purchase players as any other league does. “In the end, the Premier League is a £6billion-a-year operation in terms of revenue and that money is spent reinvested into the pitch. All good competitions have to have revenue streams to back them up.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

Chase Anderson pitched five scoreless innings for his first win in 17 starts this season, Nolan Jones homered and the Colorado Rockies snapped a seven-game losing streak by beating the Los Angeles Dodgers 4-1 on Tuesday in the opener of a doubleheader