By Brendan Pierson (Reuters) -The U.S. government's Medicare health insurance program can begin negotiating prices for some prescription drugs this

As Kentucky Gov. Andy Beshear prepares for what could be the most hotly contested election of the year, the first-term Democrat insisted on Wednesday that he would not cede so-called family values issues to his Republican opponent. In his first sit-down interview since Tuesday's primary, Beshear also tried to contrast his steady leadership with the just-concluded bitter GOP campaign in which state Attorney General Daniel Cameron prevailed in a 12-candidate field. The governor told The Associated Press that he intends to make the general election race about helping families and not trying to “rile people up,” and he accused Cameron of doing just that in his victory speech. “I think sadly from the other side, what we saw last night and what we’ll see is name-calling, stoking division, trying to incite fear or anger or maybe even hatred. And that’s not how we’re supposed to run these elections,” Beshear said. Cameron, buoyed by an endorsement from former President Donald Trump, finished 26 percentage points ahead of his nearest rival, state Agriculture Commissioner Ryan Quarles. Trump’s former U.N. ambassador, Kelly Craft, was a disappointing third after a campaign that mostly centered around her and Cameron. The much scrutinized off-year matchup between Beshear and Cameron in November could provide insight about voter sentiment heading into the 2024 elections that will determine control of the White House and Congress. The race will test the strength of a popular Democratic governor in a Republican-dominated state who hopes the reputation he forged as the state’s consoler in chief during a tumultuous four years will be enough to propel him to a second term. Cameron, one of the most prominent Black Republicans in the country, came out swinging in a primary night speech. “The new religion of the left casts doubt on the greatness of America,” Cameron said. “They embrace a picture of this country and this commonwealth that is rooted in division, that is hostile to faith and that is committed to the erosion of our education system.” The AP reached out to Cameron for an interview, but his campaign did not immediately make him available. Beshear said he sees similarities between this year’s race and his run in 2019, when he defeated GOP Gov. Matt Bevin. "If you look at this last primary, I think that you are seeing the same nastiness, the same turning people against each other,” Beshear said. Much like that contest, Beshear said he has no plans to campaign with national Democrats, including President Joe Biden. Beshear relies on his family’s strong political brand in Kentucky, where his father, Steve Beshear, is a former two-term governor. “This is about us, not Washington, D.C. Everything you’re going to hear me talk about in this election is about our families and how we move them ahead — not right, not left, but forward," Beshear said. Biden joined Beshear to console the victims of tornadoes and flooding that hit Kentucky during the governor's first term. Asked if he was bracing for opposition ads showing pictures of him and Biden together, Beshear said, “It would be pretty callous, I think, for somebody to use photos of showing up at the toughest of times against somebody.” In his speech Tuesday night, Cameron tried to tie Beshear to Biden's immigration policies, lambasted the governor's record on crime and drugs and criticized him for vetoing legislation barring transgender girls and women from participating in school sports matching their gender identity. The Republican-led legislature overrode Beshear's veto. “A governor who will not speak out on these issues, and who will not stand up for your interests, has abdicated his responsibility to the commonwealth and is not fit to lead it any longer,” Cameron said. This year, Beshear vetoed a bill banning transgender young people from receiving gender-affirming health care. That veto also was overridden. Beshear has come under GOP criticism for the veto. Beshear said Wednesday that every youngster should be treated “as a child of God.” “At the end of the day, I think what’s been done here attacks parents’ rights, and I believe medical decisions for children are best left to their parents and not big government stepping in,” he said. Beshear said he is ready to run on a record of economic growth, support for public schools and increased help for people battling drug addiction. The governor noted that hundreds of Kentucky National Guard soldiers have been deployed to the nation’s southwest border during his term in office. Kentucky will continue to “do our part when asked,” he said, declaring that “border security is national security.” He pointed to advances in providing clean drinking water to Kentuckians and getting a new Ohio River bridge built to ease traffic congestion between Cincinnati and northern Kentucky. A bridge “isn’t red or blue, it’s just really important for our families,” the governor said. Beshear now faces an electorate that has turned increasingly Republican since he won the office. He said voters will hear a message from him driven by faith and values, not partisan politics. “For me, my values are rooted in my faith,” Beshear said. “And my faith teaches me that we’re supposed to live with love and compassion, not anger and division." Cameron is the first major-party Black nominee for governor in Kentucky’s history. "To anyone who looks like me, know that you can achieve anything," he said after winning the nomination. To Beshear, "it's taken far too long to have a Black nominee of either party for governor. But I think what the attorney general said last night is right, that in this campaign people are going to judge us by our record and our values." Read More Ukraine war’s heaviest fight rages in east - follow live Charity boss speaks out over ‘traumatic’ encounter with royal aide VIDEO FOR YOU: Kentucky Gov. Beshear discusses jobs, his campaign and abortion AP News Digest 3:30 am AP News Digest 3:20 am

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Centenarians tend to have lower levels of glucose, creatinine and uric acid from their sixties onwards, according to the largest study of its kind that may lead to a simple blood test to predict a person’s chance of reaching 100. The research, published on Monday in the journal GeroScience, is the biggest to date to measure and follow up the levels of different molecules in the blood of people born between 1893 and 1920. Scientists, including those from Karolinska Institutet, assessed the data on blood molecules from over 44,500 Swedes who underwent clinical testing between 1985 and 1996 and followed up till 2020. They focused specifically on people born between 1893 and 1920, who were between 64 and 99 years old when their blood samples were first tested, and followed them up as they grew closer to 100 years of age. About 1,200 individuals in the study, or about 2.7 per cent of the participants, reached 100. Researchers compared this subset’s data with those of their peers who were younger than them. The analysis found 12 blood-based molecules associated with metabolism, inflammation as well as liver and kidney function, that were also linked to ageing or mortality in previous studies. These molecules included total cholesterol and glucose as markers of metabolism, uric acid indicating inflammation levels, enzymes indicative of liver health and creatinine as a measure of kidney health. Researchers also looked at albumin and iron levels in the blood. Except for a liver enzyme and albumin, all other molecules were found linked to the likelihood of a person becoming a centenarian. Those with increased levels of total cholesterol and iron had a greater likelihood of becoming centenarians compared to those with lower levels. However, for molecules including glucose, creatinine, uric acid, and liver enzymes, lower levels were associated with higher chances of living past 100. “We found that, on the whole, those who made it to their hundredth birthday tended to have lower levels of glucose, creatinine and uric acid from their sixties onwards,” researchers wrote in The Conversation. “Very few of the centenarians had a glucose level above 6.5 earlier in life, or a creatinine level above 125,” they said. While the differences found in the study between groups were small in some cases, researchers said the findings still suggest a “potential link” between metabolism, nutrition and longevity. However, the study falls short of recommending lifestyle factors or genes responsible for these blood molecule levels. “While chance likely plays a role for reaching age 100, the differences in biomarker values more than one decade prior death suggest that genetic and/or lifestyle factors, reflected in these biomarker levels may also play a role for exceptional longevity,” scientists wrote in the study. “However, it is reasonable to think that factors such as nutrition and alcohol intake play a role. Keeping track of your kidney and liver values, as well as glucose and uric acid as you get older, is probably not a bad idea,” they said. Read More Good financial planning could increase life expectancy, study suggests Scientists find gene that grants long life – and successfully test it on another species Scientists extend mice lives by connecting their blood to young ones

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