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The possible link between repetitive heading and cognitive impairment in later life has again been highlighted in new data published on Monday. The University of Nottingham’s FOCUS study, co-funded by the Football Association and the Professional Footballers’ Association, gathered information on heading frequency from 459 retired players aged 45 and over. Players who recalled heading a ball 15 times or more per match or training session were found to be 3.53 times more likely to score below the test threshold in the cognitive status assessment than players who said they headed the ball up to five times, the FOCUS study found. Players who recalled heading a ball six to 15 times were also 2.71 times more likely to score below the test threshold than the lowest-frequency heading group. The study said its findings suggested “repetitive heading during a professional soccer career is associated with an increased risk of cognitive impairment in later life”. It concluded further study was required to establish the upper threshold for heading frequency to mitigate this risk. The FA has already taken steps to reduce the possible risk posed by repetitive exposure to heading by issuing guidance for players in children’s and adults’ game. Adults at grassroots and professional level are now advised to perform a maximum of 10 ‘higher force’ headers per week in training. As well as restrictions on heading in training for under-18s football, the FA is entering the second season of trialling the complete removal of heading in under-12s football. FA chief executive Mark Bullingham said on the FOCUS Study: “This study is another step in understanding any potential link between neurogenerative disorders and former professional footballers. “Since funding the FIELD study, we have continued to invest in research to gain a greater understanding of the area and potential risk factors. “More research is required to fully understand the issues and we welcome a global approach to do that. “Whilst there is no doubt of the overall benefit to health of playing football, by addressing potential risk factors whilst we continue to invest in medical research, we will ensure that millions can continue to enjoy our national sport.” The FIELD study found in 2019 that footballers were three and a half times more likely to die of neurodegenerative disease compared to age-matched members of the general population. The first part of the FOCUS study, published in June, found 2.8 per cent of retired professional footballers in its study reported medically diagnosed dementia and other neurodegenerative disease compared to 0.9 per cent of controls. This meant former professionals were found to be 3.46 times more likely to have neurodegenerative diseases compared to the control group. The study also showed retired footballers in the study were twice as likely to fall below established thresholds in some dementia testing than the general population. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Leon Taylor hails ‘coming of age’ moment for Team GB’s female divers Cameron Smith has no point to prove defending Open title he won before LIV move An in-depth look at the rapid rise of Wimbledon champion Carlos Alcaraz

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England reached a Women’s World Cup semi-final for the first time on this day in 2015 after holding on to beat tournament hosts Canada 2-1 in Vancouver. Early goals from Jodie Taylor and Lucy Bronze set the Lionesses up for a historic win, but they were forced to dig deep after Christine Sinclair pulled one back for Canada just before half-time. It was the first time a senior England side – men or women – had reached the World Cup’s last four since 1990. The Lionesses had won a World Cup knockout game for the first time by defeating Norway 2-1 in the last-16 and followed it up against the Canadians in front of a crowd of 54,027 at BC Place. Taylor gave England an 11th-minute lead when she pounced on Canada skipper Lauren Sesselmann’s slip and raced on to drill a low angled finish into the bottom corner. The Lionesses extended their lead three minutes later. Fara Williams’ diagonal free-kick into the penalty area picked out Bronze and the full-back’s header bounced down over the line after hitting the crossbar. Canada lifted the home support by reducing the deficit three minutes before the interval when England goalkeeper Karen Bardsley failed to hold on to Ashley Lawrence’s cross and Sinclair turned home the rebound. Taylor was denied a second goal after the restart as her goal-bound curling effort forced a brilliant save from Canada goalkeeper Erin McLeod. England’s World Cup dream was halted in agonising fashion in their semi-final, as defender Laura Bassett’s stoppage-time own goal clinched a 2-1 win for Japan, who went on to lose 5-2 to the United States in the final. The Lionesses secured a third-place finish after beating fellow semi-final losers Germany 1-0 after extra-time thanks to Williams’ 108th-minute penalty. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

Sepsis is an illness that affects nearly 50 million people worldwide each year, with around 11 million deaths attributed to the condition. In the United States, at least 1.7 million adults in the US develop sepsis annually, and nearly 270,000 die as a result, the Centres for Disease Control and Prevention (CDC) says. It affects 245,000 people in the UK each year, with around 48,000 deaths, according to the UK Sepsis Trust. World Sepsis Day commemorated on 13th September every year, strives to raise global awareness of the life-threatening condition. The day is seen as “an opportunity for people worldwide to unite in the fight against sepsis,” the Global Sepsis Alliance says. Here is everything you need to know about sepsis: What is sepsis? Sepsis Research says when the condition strikes, the immune system “overreacts” and begins to attack the infection and everything else around it “including the body’s own tissues and organs.” “Any type of infection — bacterial, viral or fungal — can lead to sepsis,” it adds. When sepsis occurs, it can cause inflammation and cause blood clotting around the body, if it does not get treated, it can result in death, organ failure and tissue damage, CDC says. Sepsis cannot be caught from another person, the NHS explains. What are the symptoms? The World Health Organisation (WHO) explains that the condition is a “medical emergency,” so if you think a person is exhibiting signs of sepsis or if you are showing signs – make sure you call 999 or go to the emergency room immediately. According to WHO, common signs and symptoms include: • Fever or low temperature and shivering • Confusion • Difficulty breathing • Clammy or sweaty skin • Extreme body pain or discomfort • High heart rate, weak pulse or low blood pressure • Low urine output Symptoms in children include: • Fast breathing • Convulsions • Pale skin • Lethargy • Difficulty waking up • Feeling cold to touch What are the causes? The Mayo Clinic says any type of infection can lead to sepsis and those that more commonly cause the condition include infections of: • Lungs, such as pneumonia • Kidney, bladder and other parts of the urinary system • Digestive system • Bloodstream • Catheter sites • Wounds or burns “Sepsis often presents as the clinical deterioration of common and preventable infections such as those of the respiratory, gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently under-diagnosed at an early stage - when it still is potentially reversible,” the Global Sepsis Alliance says. Who is most at risk? The people most at risk of the condition, according to Mayo Clinic, are: • People with lower immune response, such as those being treated for cancer • People with human immunodeficiency virus (HIV). • People with chronic diseases such as diabetes kidney disease or chronic obstructive pulmonary disease (COPD). • people who are in intensive care or longer hospital stays. • People over the age of 65 • Infants How many cases are there globally? The WHO says a scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20 per cent of all global deaths. That same year, almost half of all global sepsis cases occurred among children with an estimated 20 million cases and 2.9 million global deaths in children under 5 years of age. How can it be prevented? The Global Sepsis Alliance says the best to to avoid sepsis is by preventing infection. This can be done by undergoing vaccinations, ensuring that you only come into contact with clean water, washing your hands properly and if you are giving birth - making sure it is in a clean and sterilised environment. Can sepsis be treated? Sepsis can be treated with appropriate treatment such as antibiotics – this should be given as soon as possible. The CDC says sometimes “surgery is required to remove tissue damaged by the infection”. “Antibiotics are critical tools for treating life-threatening infections, like those that can lead to sepsis,” the CDC adds. Read More 5 things everyone needs to know about eczema 13 potential cancer symptoms you should get checked out How can I improve my teenager’s low mood? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis Nine hours of parallel surgery: how Britain’s first womb transplant was carried out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’