World champions Argentina rested Lionel Messi but still shined in a 3-0 victory over 10-man Bolivia in La Paz on Tuesday to maintain their winning start...

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Sepsis is an illness that affects nearly 50 million people worldwide each year, with around 11 million deaths attributed to the condition. In the United States, at least 1.7 million adults in the US develop sepsis annually, and nearly 270,000 die as a result, the Centres for Disease Control and Prevention (CDC) says. It affects 245,000 people in the UK each year, with around 48,000 deaths, according to the UK Sepsis Trust. World Sepsis Day commemorated on 13th September every year, strives to raise global awareness of the life-threatening condition. The day is seen as “an opportunity for people worldwide to unite in the fight against sepsis,” the Global Sepsis Alliance says. Here is everything you need to know about sepsis: What is sepsis? Sepsis Research says when the condition strikes, the immune system “overreacts” and begins to attack the infection and everything else around it “including the body’s own tissues and organs.” “Any type of infection — bacterial, viral or fungal — can lead to sepsis,” it adds. When sepsis occurs, it can cause inflammation and cause blood clotting around the body, if it does not get treated, it can result in death, organ failure and tissue damage, CDC says. Sepsis cannot be caught from another person, the NHS explains. What are the symptoms? The World Health Organisation (WHO) explains that the condition is a “medical emergency,” so if you think a person is exhibiting signs of sepsis or if you are showing signs – make sure you call 999 or go to the emergency room immediately. According to WHO, common signs and symptoms include: • Fever or low temperature and shivering • Confusion • Difficulty breathing • Clammy or sweaty skin • Extreme body pain or discomfort • High heart rate, weak pulse or low blood pressure • Low urine output Symptoms in children include: • Fast breathing • Convulsions • Pale skin • Lethargy • Difficulty waking up • Feeling cold to touch What are the causes? The Mayo Clinic says any type of infection can lead to sepsis and those that more commonly cause the condition include infections of: • Lungs, such as pneumonia • Kidney, bladder and other parts of the urinary system • Digestive system • Bloodstream • Catheter sites • Wounds or burns “Sepsis often presents as the clinical deterioration of common and preventable infections such as those of the respiratory, gastrointestinal and urinary tract, or of wounds and skin. Sepsis is frequently under-diagnosed at an early stage - when it still is potentially reversible,” the Global Sepsis Alliance says. Who is most at risk? The people most at risk of the condition, according to Mayo Clinic, are: • People with lower immune response, such as those being treated for cancer • People with human immunodeficiency virus (HIV). • People with chronic diseases such as diabetes kidney disease or chronic obstructive pulmonary disease (COPD). • people who are in intensive care or longer hospital stays. • People over the age of 65 • Infants How many cases are there globally? The WHO says a scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for almost 20 per cent of all global deaths. That same year, almost half of all global sepsis cases occurred among children with an estimated 20 million cases and 2.9 million global deaths in children under 5 years of age. How can it be prevented? The Global Sepsis Alliance says the best to to avoid sepsis is by preventing infection. This can be done by undergoing vaccinations, ensuring that you only come into contact with clean water, washing your hands properly and if you are giving birth - making sure it is in a clean and sterilised environment. Can sepsis be treated? Sepsis can be treated with appropriate treatment such as antibiotics – this should be given as soon as possible. The CDC says sometimes “surgery is required to remove tissue damaged by the infection”. “Antibiotics are critical tools for treating life-threatening infections, like those that can lead to sepsis,” the CDC adds. Read More 5 things everyone needs to know about eczema 13 potential cancer symptoms you should get checked out How can I improve my teenager’s low mood? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis Nine hours of parallel surgery: how Britain’s first womb transplant was carried out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’

A string of murders in the Portland, Oregon metro area that police previously said were unrelated have now been linked as authorities identified a person of interest. Deputies in nine different police departments released a joint statement on Monday saying the deaths of four women who were found either near or on the sides of roads between February and May are somehow connected. The women have been identified as Kristin Smith, 22, Charity Lynn Perry, 24, Bridget Leann (Ramsay) Webster, 31, and Ashely Real, 22. Police haven’t identified the person of interest linking the deaths yet or filed any charges. Local media sites have identified the alleged person at the center of the investigation, but this information is unconfirmed. Read More Deaths of four women in Portland linked to person of interest, authorities say

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Cyberattacks by the UK’s enemies are becoming “relentless” as we enter a “new era” of global conflict, an expert has warned. It comes after Russian hackers allegedly acquired top-secret security information on some of the country’s most sensitive military sites, including the HMNB Clyde nuclear submarine base on the west coast of Scotland and the Porton Down chemical weapon lab. The “potentially very damaging” attack last month by hacking group LockBit, which has known links to Russian nationals, saw thousands of pages of data leaked onto the dark web after private security firm Zaun was targeted, the Sunday Mirror newspaper reported. The company, which provides security fencing for sites related to the Ministry of Defence, said it had been the victim of a “sophisticated cyber attack”. Responding to the news, Kevin Curran, professor of cyber security at Ulster University, told the PA news agency that LockBit’s attack was “serious” as we approach a potential “World War Three” following Russia’s invasion of Ukraine. He said the raid was “likely” sponsored by the Russian state given the nature of its target and that cyber attacks by Britain’s enemies had become “relentless”. Professor Curran warned that we were unprepared for this new era as third-party companies, which hold data on our military infrastructure were not being properly regulated. He said: “You can’t just expect third-party suppliers to adhere to your rules. “There is always a risk when you have third-party suppliers and you do wonder if they adhere to industry best practice. “It is a worry because everything is online now – cybercrime is the biggest crime in the world. “Given the new era we are entering which is the brink of World War Three everything is serious. They are relentless with these attacks Professor Kevin Curran “They are relentless with these attacks. Their best way into our country is through our cyber-security. This is the nation at risk. “In this case, given the target, my money would be on this being state-sponsored.” It comes after Labour MP Kevan Jones, who sits on the Commons Defence Select Committee, urged the Government to explain why Zaun’s computer systems were “so vulnerable”, warning: “This is potentially very damaging to the security of some of our most sensitive sites.” “Any information which gives security arrangements to potential enemies is of huge concern,” he added. The government has so far declined to respond to concerns, with a spokesperson saying: “We do not comment on security matters.” In a statement on its website published on Friday, Zaun said it had taken “all reasonable measures to mitigate any attacks on our systems” and explained that they had referred the matter to the National Cyber Security Centre (NCSC). It explained that the breach occurred through a “rogue Windows 7 PC” that was running software for one of their manufacturing machines but that the network was “otherwise up to date”. It said: “At the time of the attack, we believed that our cyber-security software had thwarted any transfer of data. “However, we can now confirm that during the attack LockBit managed to download some data, possibly limited to the vulnerable PC but with a risk that some data on the server was accessed. “It is believed that this is 10 GB of data, 0.74 per cent of our stored data. “It is well known that Zaun is a specialist in high-security perimeter fencing and has supplied fencing to many high-profile sites. “Sites where our products are used include prisons, military bases and utilities.” Zaun has been approached for further comment. Read More Ukraine-Russia war – live: Putin suffering ‘mounting casualties’ and forced to appeal for foreign fighters Russia attacks a Ukrainian port before key grain deal talks between Putin and Turkey's president Russians press Ukraine in the northeast to distract from more important battles in counteroffensive Ukraine ‘targets critical bridge’ built by Putin as counteroffensive ‘breaks through on southern front’ Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

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A woman who says that the recently detained person of interest in the suspected Oregon serial killer case Jesse Lee Calhoun lived with her and her children for a year and a half, has shared allegations that there may have been connections between the 38-year-old and some of the victims. In a video interview shared on YouTube, Krista Senor said Calhoun was linked to at least two of the four murdered women and that he had sex and sold fentanyl to other women during their relationship, according to Oregon Live. “I’m still in shock over this. It’s just surreal,” Ms Sinor, 43 told The Oregonian on Wednesday. “It’s very strange. I can’t wrap my mind around any of it. Neither can his family or friends.” Police spent three days searching her apartment in Milwaukie, Oregon after they arrested Calhoun on 6 June. Former Oregon Governor Kate Brown commuted Calhoun’s sentence for several burglaries on 23 June 2021, about a year before he was set to be released, for his work fighting wildfires. Ms Sinor said Calhoun was connected to two of the victims, Ashley Real, 22, from Portland, and Bridget Leann Ramsey Webster, 31, from Milwaukie. The other two victims are Charity Perry and Kristin Smith – police said on Monday 17 July that their deaths are connected and that a person of interest had been identified. “No charges have been filed against anyone in connection with any of these four death investigations,” the Multnomah County District Attorney’s Office and law enforcement agencies said in a press release. “Investigators have interviewed multiple people in connection with these cases and have identified at least one person of interest that is linked to all four of the decedents.” A man who saw Calhoun being arrested told KGW that “There’s craziness in the world. You hope it doesn’t happen too often. It was pretty nuts to see it happen in my backyard”. Calhoun was arrested on 6 June as he and his girlfriend were at a gas station in Milwaukie. The arrest didn’t occur without incident. “I don’t know how he made it through the 10 officers but he made it through and across traffic and down to the river and hopped in,” the witness told KGW. “I was like, ‘I wonder what this guy did,’” the witness added. “It seems whatever he did was really important — or required that much law enforcement, I should say.” The four women were all found dead across the region since the middle of February. Ms Sinor said in the YouTube interview that Calhoun and Ms Real had been seeing each other on and off for about a year and that he would provide Ms Webster with drugs in exchange for sex, but Ms Sinor added that she didn’t know how Calhoun was linked to Ms Perry or Ms Smith. When Ms Sinor was asked if Calhoun is a serial killer, Ms Sinor said “My first thought is that maybe a fentanyl overdose and he freaked out”. “He’s a family guy. He seems like a family guy. He’s really close with his family and he would do anything for them and stuff but like my kids ... he loves my kids and my kids love him,” she added in the YouTube interview, according to KGW. The witness who saw Calhoun being arrested told KGW: “I don’t want to see him come out from bars ever again.” Read More Portland ‘serial killer’ – live: Jesse Calhoun got prison pardon for fighting wildfires before deaths of women An inmate was pardoned by Oregon’s governor. Two years on he’s a person of interest in four suspicious deaths Jesse Calhoun identified as person of interest in suspicious deaths of four women in Portland

Students of the New College of Florida have planned to host an alternative graduation ceremony to oppose what they said was the “hostile takeover” of the institution through conservative trustees appointed by Ron DeSantis earlier this year. The graduation, which will be separate from the official ceremony, is being organised by New College seniors, with support from the alumni-run Novo Collegian Alliance, which has a little more than $105,000 of the $130,000 funding goal for the ceremony through their GoFundMe page. Called “[New] Commencement: On Our Terms”, the event “is an alternative commencement and grad celebration led by students, for students, and against the hostile takeover of New College of Florida”, according to the GoFundMe page. Governor DeSantis appointed six new members to the Board of Trustees in January, leading to backlash from students who opposed the views of the conservatives. The tapping of Scott Atlas as the speaker for the graduation ceremony on Friday also became a flashpoint between students and the administration. A controversial figure, Dr Atlas served as top adviser to Donald Trump during the Covid-19 pandemic and often provided views contradictory to medical professionals. The board, however, hailed his resume as “impressive” while announcing him as the speaker at the commencement ceremony. “Dr Atlas’s perspective and resume are impressive; he is a champion and fighter for free speech and a renowned national leader,” said Richard Corcoran, the school’s president, in a statement. “We are happy to welcome him here at New College, where we place a high value on personal freedom and individual autonomy, as Dr Atlas does.” In their alternative commencement ceremony, scheduled for Thursday, the students invited Maya Wiley, an attorney and CEO of the Leadership Conference on Civil and Human Rights, as the keynote speaker. The event will be followed by a private gathering on 19 May at an undisclosed location, reported the Sarasota Herald-Tribune. “We’re now guaranteed a graduation surrounded by the New College community members that truly want to celebrate who we are, rather than those attempting to change our culture,” Madison Markham, a graduating senior and one of the students planning the event, was quoted as saying by Politico. According to the outlet, while the students opposed the changes brought by Mr DeSantis, they were unable to have a significant impact on them. The moves by the board included the removal of school’s president Patricia Okker, and replacing her with Mr Corcoran, a former Republican House Speaker, who earns $699,000 annually, more than double his predecessor, as per the Sarasota Herald-Tribune. At least five faculty members have been denied tenure, prompting one of the trustees to quit the board and resign as a professor from the university, reported Politico. “The new administration that has spent the past four months attacking our students and community cannot, in good faith, celebrate our graduating students and their accomplishments,” said the GoFundMe page. “Commencement is supposed to be a celebration of graduating students and the people who have shaped this school to be what it is. And we’re proud of who we are! So, we’re taking the celebration plans into our own hands,” it said. “We want this event to be a fulfilling and memorable experience for graduating students that keeps the focus on STUDENTS, rather than an administration desperately trying to maintain normality and instill conformity.” Read More DeSantis criticizes Trump for implying Florida abortion ban is 'too harsh' Florida teacher under investigation for showing Disney movie with LGBT+ character speaks out How Republicans and right-wing media turned Jordan Neely’s killer into a hero US seeks dismissal of corruption charges against Florida 2018 Democratic governor nominee Gillum Trump and DeSantis to court Iowa voters at duelling events today

Asset managers trimmed bearish positions on the yen by the most in more than three years as inflation

The slump in dealmaking cut pay for investment bankers at almost every level of seniority in London last