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Could bats hold the secret to beating Covid and cancer?
Bats could hold the key to unlocking new ways to combat cancer, a new study suggests. A paper published by Oxford University Press, looks at the rapid evolution of bats for their abilities to both host and survive infections such as Covid-19 as well as cancer. The animals are known to have a strong immune system which helps fight off many viruses and diseases. These mammals are also thought to have played a role in the emergence of Covid-19 and scientists say such characteristics are interesting to investigate due to the implications it might have on human health. According to the research, understanding the mechanisms of the bat’s immune system that allows these animals to fight off viral infections – may pave the way to understanding how to prevent disease outbreaks from animals to people. To conduct the study, researchers sequenced the genomes of two bat species - the Jamaican fruit bat and the Mesoamerican mustached bat. The team used advanced technology from Oxford Nanopore Technologies and bat samples collected by the American Museum of Natural History in Belize. They then compared the bat genomes to those of other mammals. The results revealed that bats possessed genetic adaptations in proteins which are related to DNA repair and cancer suppression. It was found that bats had adaptations in six DNA repair-related proteins and 46 cancer-related proteins. The study also found that bats had more than double the number of altered cancer-related genes compared to other mammals, which provided further evidence that they have the ability to suppress cancer. “By generating these new bat genomes and comparing them to other mammals we continue to find extraordinary new adaptations in antiviral and anticancer genes,” said the paper’s lead author, Armin Scheben. “These investigations are the first step towards translating research on the unique biology of bats into insights relevant to understanding and treating ageing and diseases, such as cancer, in humans.” The results open up new paths for understanding and studying the links between cancer and immunity, which offers hope that these insights from bats might possibly lead to new treatments for human illnesses. According to the United States Department of the Interior, there are over 1,400 species of bats worldwide and are mostly found in extreme deserts and polar regions. In the US and Canada, there are about 45 species of bats. Read More British bats ‘can help identify coronaviruses with potential to infect humans’ Coronavirus origins still a mystery 3 years into pandemic Groundbreaking migraine treatment offers ‘new hope’ for patients World Sepsis Day: What is the condition and its symptoms? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis
2023-09-20 22:28
Wells Fargo CFO expects upside in net interest income
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2023-06-13 21:51
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2023-06-21 08:00
This renowned explorer built a career rescuing people from caves. Now he’s stuck in one of the world’s deepest
For five days, expert cave explorer Mark Dickey has been stuck 3,400 feet below the surface in a cave in the Taurus Moutain region of Turkey. Mr Dickey, 40, is an experienced caver who embarked on an expedition mission to map one of the deepest caves in the world – the Morca cave system in southern Turkey. But the expedition was suddenly cut short after Mr Dickey fell ill with gastrointestinal bleeding. Now, a rescue team of over 150 personnel from several international organisations have combined their efforts to try to retrieve Mr Dickey, who cannot leave the cave due to the emergency medical situation. As of Thursday, officials in the Speleological Federation of Turkey said that Mr Dickey’s situation had improved but that he would require a stretcher, making the rescue mission even more complicated. An expert caver Hailing from Croton-on-Hudson, New York, Mr Dickey is a highly-trained caver, cave rescuer himself and well-known in the international speleological (cave expert) community, according to the European Cave Rescue Association (ECRA). His resume of cave explorations and expert status is endless: secretary of the ECRA medical committee, lead instructor for Caving Academy, a US-based organisation that prepares other cavers for exploration and a national instructor for the National Cave Rescue Commission. He also volunteers with the New Jersey Initial Response Team, a nonprofit search-and-rescue team. Having participated in many cave explorations in karst areas around the world for many years, Mr Dickey is knowledgeable and skilled – the kind of person you’d want on complicated cave exploration like the Morca mission. Mr Dickey was on an expedition to map the 4,186-foot-deep cave system in southern Turkey for the Anatolian Speleology Group Association. Photos from a Facebook page that seemingly belongs to Mr Dickey show him happily preparing for the mission by inspecting all the necessary gear before embarking. But what Mr Dickey, and others, could not prepare for was the sudden emergency medical situation he found himself in during the journey. On 2 September, Mr Dickey fell ill with severe gastric pain that was escalating quickly. Though there was initial hope that Mr Dickey could exit the cave on his own, the pain turned into gastrointestinal bleeding and it was clear he needed medical attention quickly. The Speleological Federation of Turkey sent a medical team and six units of blood in the following days in the hopes of stabilising Mr Dickey’s medical situation. On Thursday, Mr Dickey appeared in a video for the first time, obtained by The Associated Press, where he thanked Turkish authorities for responding quickly to his medical needs. “I don’t quite know what’s happened, but I do know that the quick response of the Turkish government to get the medical supplies that I need, in my opinion, saved my life,” Mr Dickey said. “I was very close to the edge.” While doctors worked to assist Mr Dickey, cave experts began putting their teams together to figure out how to rescue Mr Dickey through one of the deepest, and very complicated, cave systems. “A long and challenging rescue operation is initiated to carry Mark out on a stretcher,” the ECRA said in a statement. A complicated route Teams from Turkey, Hungary, Bulgaria, Croatia, Italy and Poland are working to create a path out of the cave system. The Morca cave system descends through various, very narrow, twists, turns and rappels – making it a difficult exploration for any person in good health. The underground equivalent of the cave is like climbing Mount Everest. “It takes a full 15 hours for an experienced caver to reach the surface in ideal conditions,” the Speleological Federation of Turkey said. To tackle the issue, the team of international experts has divided up the depths of the cave and assigned it to a specific team to figure out a solution for that specific area. At multiple very narrow spots, a demolition team will need to widen them so Mr Dickey can pass through on a stretcher. They will also need to set up several camp spots on the way up to continuously monitor Mr Dickey and give him and his team sections to rest in. To make the matter more complicated, communication between the underground team and the surface team is limited. Runners are being used to travel from the camp where Mr Dickey is to the surface where a telephone line is to speak with officials, according to AP. Hungarian Cave Rescue Service member, Marton Kovacs, told CBS News that they were also addressing the danger of falling rocks in several places. The Hungarian team is working between the 590 to 1180-feet depths Mr Kovacs said Mr Dickey’s exit will take several days and they hope to begin on Saturday or Sunday depending on Mr Dickey’s condition. Read More Trapped American explorer says he was ‘very close to the edge’ in emotional first video from Turkish cave American explorer trapped 3,400 feet in Turkey cave shares emotional video as rescue effort drags on - latest Dramatic rescue underway for renowned American caver stuck 3,700 feet underground Trapped American explorer releases emotional video from deep in Turkish cave Explorer Mark Dickey trapped 3,400 feet in Turkey cave shares emotional video Peter Navarro found guilty of contempt of Congress for defying Jan 6 committee
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Clients, Banking Partners Retreat From Odey After Allegations
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Britain wants to work constructively with Meta over encryption -Braverman
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What did Halle Berry say about aging? 'Moonfall' star recently celebrated her 57th birthday
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2023-08-29 04:29
Zhang makes history to send Ruud crashing out of US Open
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2023-08-31 10:16
Was Nate Diaz injured before his bout against Jake Paul? ‘My goal is to get a rematch’
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2023-08-07 14:25
Puma sticks to full-year profit forecast despite drop in Q3 earnings
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2023-10-24 14:59
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