By Samuel Indyk and Rae Wee LONDON The pound was on track for its biggest one-day gain in

By Granth Vanaik DoorDash forecast fourth-quarter core profit above estimates after topping quarterly revenue expectations on Wednesday, boosted

One euro homes in Italy are two a penny, so Jeffrey Pfefferle and Leon McNaught bought two. They snapped up their first cheap turnkey property in Mussomeli, Sicily. But the locals were so friendly that they decided to buy another.

England will face Chile in the Rugby World Cup this afternoon at Stade Pierre-Mauroy in Lille. Steve Borthwick’s side will be hoping to record a third victory after last weekend’s scrappy bonus-point win against Japan and their opening defeat of Argentina. Owen Farrell returns from his red-card ban alongside 12 other changes, including Marcus Smith at full back, as England aim to give squad members who have featured less so far a good run out. England currently sit top of Pool D with nine points after their first two wins and a win would all but secure a quarter-final place. Los Condores lost their first two matches in what is their first Rugby World Cup and currently sit 22nd in the world rankings compared to England’s sixth. They are currently at the bottom of Pool D with zero points. Follow all of the action here live from Stade Pierre-Mauroy. Plus get the latest Rugby World Cup odds here and tips on England vs Chile here. Read More Marcus Smith backed to shine at full-back as England tackle unfancied Chile Owen Farrell recalls emotional roller-coaster ride of exile from England team

Our canine companions could soon be enjoying much longer lifespans, if a drug which claims it can extend dogs’ lives eventually gets approved. The drug, made by a tech firm in California, just cleared a vital hurdle to doing just that, after it got partial approval by regulators in the US. Loyal, a San Francisco-based company founded in 2020, has been researching how it can increase dogs’ lifespans – in particular larger breeds, which tend to die younger. Large and “giant” breeds tend to live to between eight and 12 years. Smaller dogs, such as Chihuahuas, can keep going to the ripe old age of 20. Loyal’s main product, the catchily-titled LOY-001, is designed not only to extend dogs’ lives but also maintain their quality of life. Now, it has passed the “reasonable expectation of effectiveness” test, set by regulators at the US’ Food and Drug Administration. Loyal’s chief executive, Celine Halioua, said: "Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs. "This milestone is the result of years of careful work by the team. We'll continue to work just as diligently to bring this and our other longevity programs through to FDA approval." Selective breeding of dogs has caused higher levels of hormones which help the animals grow faster. That is also believed to reduce their lifespan, the company said. Big dogs tend to have more of this hormone than their smaller counterparts. Animal rights activists are not yet convinced. Some experts fear it will only serve to extend animals’ suffering. Loyal, on the other hand, says the drug aims to treat doggy diseases which are associated with ageing through preventing them, rather than waiting for the animals to get sick before treating them. The company said that the drug could be available to US customers as early as 2026. So that’s plenty of time for walkies between now and then. How to join the indy100's free WhatsApp channel Sign up to our free indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

NEW ORLEANS (AP) — Karl-Anthony Towns capped a 29-point performance with a running floater off the glass with 5 seconds left, and the Minnesota Timberwolves overcame a 14-point deficit in the final 7:32 to beat the New Orleans Pelicans 121-120 on Saturday night.

The Ballon d’Or awards ceremony takes place at the Theatre du Chatelet in Paris this evening when football’s most prestigious prize is presented to the best footballer from the 2022/23 season. Lionel Messi, the favourite to win the Ballon d’Or, is the most decorated winner of all time with seven triumphs to his name. His heroics in helping Argentina win the World Cup mean Messi looks likely to extend his record with an eighth win but he faces competition from Manchester City’s Erling Haaland who had a record-breaking season of his own and PSG’s Kylian Mbappe after he won Ligue 1 and played a huge part in taking France to the World Cup final. The women’s award, the Ballon d’Or Féminin, will also be handed out this evening. Spain’s Aitana Bonmati is the favourite to succeed Alexia Putellas as the award winner after leading Spain to their Women’s World Cup triumph and Barcelona to the Women’s Champions League but there may be some surprises in store at the ceremony. Follow along for the latest updates from the Ballon d’Or awards in Paris with our liveblog below:

Officials say three U.S. military personnel have been taken to a hospital, one with critical injures, after a U.S. aircraft crashed on a north Australian island during a multination military exercise

As the hosts enjoyed a moment in the Plaza, a Carrie Underwood song filled the airwaves

Wolfsburg defender Micky van de Ven is set to undergo a medical with Tottenham ahead of a switch to the Premier League, 90min understands.

A container ship owned by an Israeli billionaire came under attack by a suspected Iranian drone in the Indian Ocean as Israel wages war on Hamas in the Gaza Strip

US Deputy Treasury Secretary Wally Adeyemo said China’s economic issues are proving to be a headwind for the